Publications by authors named "Rukiye Yasak Guner"

Acne vulgaris (AV) is a chronic inflammatory skin condition predominantly observed during adolescence. Interoception accuracy (IAc) refers to the ability to perceive internal bodily states such as hunger and thirst. Since the brain and skin originate from the same embryological layer, the ectoderm, it is hypothesized that skin changes and disorders might affect individual perceptions.

View Article and Find Full Text PDF
Article Synopsis
  • Pemphigus vulgaris (PV) is an autoimmune disease mainly affecting the mouth, leading to symptoms like burning sensations and oral erosions.
  • A study of 106 patients showed that most had the mucocutaneous subtype, with many experiencing severe symptoms that significantly impacted their quality of life.
  • Treatment often involved systemic steroids and rituximab, with a complete response seen in those taking rituximab, emphasizing the importance of monitoring the disease’s effects on patients' lives.
View Article and Find Full Text PDF

Introduction: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening acute mucocutaneous disorders usually triggered by drugs. In this study, we aimed to evaluate the factors affecting mortality in patients with SJS-TEN.

Methods: Our study is a retrospective cohort study, analyzing data collected from a total of 12 tertiary care centers between April 2012 and April 2022.

View Article and Find Full Text PDF

Background: Pyoderma Gangrenosum (PG) is a chronic disease characterized by recalcitrant skin ulcers.

Objective: We aimed to evaluate the demographic, clinical characteristics, treatments and factors affecting the treatment responses of patients with PG.

Methods: We performed a multicenter study of 12 tertiary care centers.

View Article and Find Full Text PDF

Objective: Seborrheic dermatitis (SD) is a chronic inflammatory disease. The etiology of the disease is still unknown. The systemic immune-inflammation index (SII), red cell distribution width (RDW), mean platelet volume (MPV), C-reactive protein (CRP), monocyte to HDL cholesterol ratio (MHR), platelet to lymphocyte ratio (PLR), and neutrophil to lymphocyte ratio (NLR) have all been reported as inflammatory markers in recent studies.

View Article and Find Full Text PDF

Backgrounds: Mutation of protein-coding genes and non-coding genes is a factor in psoriasis etiology. Non-coding RNA (ncRNA), which does not have protein-coding capacity, is available in the human genome. HOTAIR (HOX Antisense Intergenic RNA) and 7SL-RNA are known as ncRNA.

View Article and Find Full Text PDF

Purpose: In the treatment of cutaneous leishmaniasis (CL), developing drug resistance, existing toxic effects of drugs and failure respond to treatment cause the need to try different treatment methods. We investigated the effect of gold-conjugated macrophage-specific antibody on amastigotes under infra-red light for the treatment of CL.

Methods: Female BALB/c (4-8 weeks old, 20 ± 5 g weight) mice were used in the study.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to determine the incidence, demographics, and clinical characteristics of pemphigoid diseases in Turkey, as existing data were limited.
  • - Researchers analyzed 295 patients diagnosed with pemphigoid over one year, finding a higher prevalence of bullous pemphigoid, which accounted for 93.2% of cases, with an overall incidence rate of 3.55 cases per million years.
  • - The study highlighted that gliptin derivative drugs might be a common trigger for bullous pemphigoid, and cardiovascular (27.8%) and neurological (23.7%) diseases were frequently observed alongside these conditions.
View Article and Find Full Text PDF

Background: Sensitive skin is subjective cutaneous hyperreactivity to environmental factors. Demodicosis is a skin disorder caused by Demodex mites. There may be a link between demodicosis and sensitive skin.

View Article and Find Full Text PDF

Acne vulgaris is a chronic inflammatory skin disease that mostly develops during adolescence and continues throughout adulthood. It affects the face, the main location of cosmetic appearance. Despite many developments in acne treatment, various combination therapies are needed to create the best option.

View Article and Find Full Text PDF