Chemopreventive Agents from Physalis minima Function as Michael Reaction Acceptors.

Background: The fruits of some varieties of genus Physalis have been used as delicious fruits and functional food in the Northeast of China.

Materials And Methods: To reveal the functional material basis, we performed bioactivity-guided phytochemical research and chemopreventive effect assay of the constituents from Physalis minima.

Results: It was demonstrated that the ethyl acetate extract of P.

Unprecedent aminophysalin from Physalis angulata.

The 95% ethanol extract of the whole plant of Physalis angulata Linn. afforded one new skeletal physalin named aminophysalin A (1) and one new naturally occurring 5β-hydroxy-6a-chloro-5,6-dihydrophysalin B (2), together with five known physalins (3-7). Their structures were elucidated through MS, IR, NMR spectroscopy analyses and X-ray crystallography.