Revealing the impact of organic selenium-enriched Lactiplantibacillus plantarum NML21 on yogurt quality through volatile flavor compounds and untargeted metabolomics.

Effective selenium supplementation strategies are essential for alleviating global selenium deficiency. This study utilized the high‑selenium-tolerant strain Lactiplantibacillus plantarum NML21 to produce selenium-enriched yogurt, successfully converting inorganic Se(IV) into organic selenium, with selenoproteins accounting for 69.52 % of the total selenium content (995.

Effect of sowing date on physicochemical properties of waxy and non-waxy proso millet (Panicum miliaceum L.) starches.

In this experiment, waxy (Shuzi, P1) and non-waxy (Ningmei No. 14, P2) proso millet were used as experimental materials to study the quality changes of waxy and non-waxy proso millet in different sowing dates as well as the differences in the physical and chemical properties of starch, such as starch morphological structure, crystal structure and gelatinization properties. The results showed that with the postponement of the sowing date, the total starch contents of P1 and P2 decreased by 2 % - 7.

TRPML1 agonist ML-SA5 mitigates uranium-induced nephrotoxicity via promoting lysosomal exocytosis.

Uranium (U) released from U mining and spent nuclear fuel reprocessing in the nuclear industry, nuclear accidents and military activities as a primary environmental pollutant (e.g., drinking water pollution) is a threat to human health.

Colistin-niclosamide-loaded nanoemulsions and nanoemulsion gels for effective therapy of colistin-resistant infections.

Colistin (COL) is regarded as a last-resort treatment for infections by multidrug-resistant (MDR) Gram-negative bacteria. The emergence of colistin-resistant Enterobacterales poses a significant global public health concern. Our study discovered that niclosamide (NIC) reverses COL resistance in via a checkerboard assay.

Associations between serum cystatin C and fall reports in an Elderly population.

Fall is common in the elderly, and chronic kidney disease is considered a major risk factor. Serum creatinine (Cre) and cystatin C (Cys C) are commonly used biomarkers for renal function, while the ratio of Cre to Cys C, known as the sarcopenia index (SI), provides insights into muscle health. This study investigates the relationships between Cre, Cys C, estimated glomerular filtration rates (eGFR), SI, and self-reported falls using National Health and Nutrition Examination Survey (NHANES) data.

Effects of Rehydration on Bacterial Diversity in the Rhizosphere of Broomcorn Millet ( L.) after Drought Stress at the Flowering Stage.

This study aimed to elucidate responses of the bacterial structure and diversity of the rhizosphere in flowering broomcorn millet after rehydration following drought stress. In this study, the broomcorn millet varieties 'Hequ red millet' (A1) and 'Yanshu No.10' (A2), known for their different drought tolerance levels, were selected as experimental materials.

Correlation between novel inflammatory markers and carotid atherosclerosis: A retrospective case-control study.

Objective: Carotid atherosclerosis is a chronic inflammatory disease, which is a major cause of ischemic stroke. The purpose of this study was to analyze the relationship between carotid atherosclerosis and novel inflammatory markers, including platelet to lymphocyte ratio (PLR), neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), platelet to neutrophil ratio (PNR), neutrophil to lymphocyte platelet ratio (NLPR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and aggregate index of systemic inflammation (AISI), in order to find the best inflammatory predictor of carotid atherosclerosis.

Method: We included 10015 patients who underwent routine physical examinations at the physical examination center of our hospital from January 2016 to December 2019, among whom 1910 were diagnosed with carotid atherosclerosis.

Distribution of LPRD in OSAHS Patients: Is There a Correlation?

Objective: Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) and Laryngopharyngeal Reflux Disease (LPRD) are interrelated medical conditions affecting the respiratory system. This article aimed to investigate the potential correlation between the two.

Methods: This cross-sectional study was carried out on a total of 52 participants diagnosed with both OSAHS and LPRD.

Fermentation of Persimmon Leaves Extract by Lactiplantibacillus plantarum and Saccharomyces cerevisiae.

Persimmon leaves usually as agricultural and forestry waste were fermented by Lactiplantibacillus plantarum and Saccharomyces cerevisiae. Growth and metabolic performances of L. plantarum and S.

Induction of lysosomal exocytosis and biogenesis via TRPML1 activation for the treatment of uranium-induced nephrotoxicity.

Uranium (U) is a well-known nephrotoxicant which forms precipitates in the lysosomes of renal proximal tubular epithelial cells (PTECs) after U-exposure at a cytotoxic dose. However, the roles of lysosomes in U decorporation and detoxification remain to be elucidated. Mucolipin transient receptor potential channel 1 (TRPML1) is a major lysosomal Ca channel regulating lysosomal exocytosis.

Zhizhu Kuanzhong, a traditional Chinese medicine, alleviates gastric hypersensitivity and motor dysfunction on a rat model of functional dyspepsia.

Zhizhu Kuanzhong (ZZKZ) is a traditional Chinese medicine modified from classic formula Zhizhu decoction in "Synopsis of Golden Chamber" (Han Dynasty in the 3 century) and the Zhizhu pill in "Differentiation on Endogenous" in Jin Dynasty (1,115-1,234). ZZKZ contains four botanical drugs, including L [Rutaceae; ], Koidz. [Compositae; ], DC [Apiaceae; ], and Bunge [Rosaceae; ], which have been widely used in clinical therapy for functional dyspepsia (FD).

Associations of serum calcium/magnesium ratios with coronary artery disease in diabetes: a cross-sectional study.

Objective: The early detection of coronary artery disease (CAD) in diabetes mellitus is a major clinical difficulty. The purpose of this paper is to find out a convenient and economical index to help to screen for patients with CAD in diabetes mellitus.

Method: From January 2019 to December 2019, a total of 1028 patients hospitalized in the general department of our hospital have been enrolled in our cross-sectional study, of which 190 were diagnosed with CAD and 314 with diabetes.

Graphene oxide modification enhances the activity of chitosan against Fusarium graminearum in vitro and in vivo.

Fusarium graminearum (F. graminearum), a pathogen for Fusarium head blight (FHB) on wheat, significantly reduces wheat yield and poses potential threats to human food safety. In this study, graphene oxide (GO) modified chitosan (GO-CS composite) was synthesized and its antifungal activity against F.

Opportunistic osteoporosis screening using chest CT with artificial intelligence.

Unlabelled: Osteoporosis has a high incidence and a low detection rate. If it is not detected in time, it will cause osteoporotic fracture and other serious consequences. This study showed that the attenuation values of vertebrae on chest CT could be used for opportunistic screening of osteoporosis.

Polyethyleneimine-reinforced Sn/Cu foam dendritic self-supporting catalytic cathode for CO reduction to HCOOH.

In this work, a novel catalytic cathode of polyethyleneimine (PEI)-Sn/Cu foam with dendritic structure was prepared by electrodeposition and impregnation. It was used in the electrocatalytic reduction of CO to HCOOH, and its performance in this process was evaluated. At -0.

EphrinB2/ephB2 activation facilitates colonic synaptic potentiation and plasticity contributing to long-term visceral hypersensitivity in irritable bowel syndrome.

Aims: Sustained visceral hypersensitivity is a hallmark of irritable bowel syndrome (IBS) could be partially explained by enteric neural remodeling. Particularly, synaptic plasticity in the enteric nervous system, a form of enteric "memory", has been speculated as a participant in the pain maintenance in IBS. This study aimed to elucidate the role of ephrinB2/ephB2 in enteric synaptic plasticity and visceral pain in IBS.

Cross-sectional association between body fat percentage and arteriosclerosis assessed by Cardio-Ankle Vascular Index in a Chinese population: a retrospective observational study.

Objective: To evaluate arteriosclerosis using Cardio-Ankle Vascular Index (CAVI) and to explore the relation between the body fat percentage (BFP) and CAVI.

Design: A retrospective observational study.

Setting And Participants: A total of 1152 patients admitted to a geriatric unit and general practice at a mega hospital in Wuhan, China, from November 2018 to November 2019 were included in this study.

Thoracic Aorta Diameter Calculation by Artificial Intelligence Can Predict the Degree of Arterial Stiffness.

Arterial aging is characterized by decreased vascular function, caused by arterial stiffness (AS), and vascular morphological changes, caused by arterial dilatation. We analyzed the relationship of pre-AS and AS, as assessed by cardio ankle vascular index (CAVI), with arterial diameters (AD) at nine levels, from the aortic sinus to the abdominal aorta, as measured by artificial intelligence (AI) on non-enhanced chest computed tomography (CT) images. Overall, 801 patients who underwent both chest CT scan and arterial elasticity test were enrolled.

Enhancing the Catalytic Properties of Mordenites via an Alkali-Acid Treatment and by Loading Nickel-Cerium during -Ethyltoluene Isomerization.

The catalytic performance of the selective isomerization of -ethyltoluene (O-ET) is crucial to increasing the -ethyltoluene (M-ET) and -ethyltoluene (P-ET) yields. During the isomerization of O-ET, traditional (commercial) mordenites (HM) are generally limited by a high reaction temperature (235 °C), as well as a low yield of the isomerization product (49.0%).

Associations between bone mineral density in different measurement locations and coronary artery disease: a cross-sectional study.

Unlabelled: The bone mineral density (BMD) loss is closely related to coronary heart disease (CAD). The BMD measured at different locations differ in BMD values, the risk to CAD, and the capability to identify CAD. An average BMD of the right and left femoral neck being below - 1.