miR-146b-5p Plays a Critical Role in the Regulation of Autophagy in ∆per -Infected RAW264.7 Cells.

-caused brucellosis is one of the most widespread worldwide zoonoses. Lipopolysaccharide (LPS) of , which functions as pathogen-associated molecular patterns (PAMPs), is an important virulence factor that elicits protective antibodies. of .

Genome-wide analysis of circular RNAs in goat skin fibroblast cells in response to Orf virus infection.

Orf, caused by Orf virus (ORFV), is a globally distributed zoonotic disease responsible for serious economic losses in the agricultural sector. However, the mechanism underlying ORFV infection remains largely unknown. Circular RNAs (circRNAs), a novel type of endogenous non-coding RNAs, play important roles in various pathological processes but their involvement in ORFV infection and host response is unclear.

Alterations of microRNAs and their predicted targeting mRNAs expression in RAW264.7 macrophages infected with Omp25 mutant Brucella melitensis.

Brucellosis is a worldwide zoonosis caused by Brucella species and represents a serious threat to both human and animal health. Omp25 is an important immunogenic and protective antigen in Brucella species; however, the functional mechanism of Omp25 in macrophages has not yet been elucidated. Here, we constructed a Brucella melitensis omp25 deletion mutant (M5-90-Δ omp25) and performed microRNA (miRNA) profiling of infected RAW264.

Upregulation of Immune Process-Associated Genes in RAW264.7 Macrophage Cells in Response to Infection.

Melioidosis is a severe and fatal tropical zoonosis, which is triggered by . To better understand the host's response to infection of , an RNA-Seq technology was used to confirm differentially expressed genes (DEGs) in RAW264.7 cells infected with .