Transcranial Magneto-Acoustic Stimulation Attenuates Synaptic Plasticity Impairment through the Activation of Piezo1 in Alzheimer's Disease Mouse Model.

The neuropathological features of Alzheimer's disease include amyloid plaques. Rapidly emerging evidence suggests that Piezo1, a mechanosensitive cation channel, plays a critical role in transforming ultrasound-related mechanical stimuli through its trimeric propeller-like structure, but the importance of Piezo1-mediated mechanotransduction in brain functions is less appreciated. However, apart from mechanical stimulation, Piezo1 channels are strongly modulated by voltage.

A Noninvasive Deep Brain Stimulation Method via Temporal-Spatial Interference Magneto-Acoustic Effect: Simulation and Experimental Validation.

Deep brain transcranial stimulation is used in both research and for the treatment of neuropsychological diseases. Ideally, such stimulation should be noninvasive and precisely controlled. We propose a temporal-spatial interference magneto-acoustic stimulation (TIMAS) method combining transcranial magneto-acoustic stimulation (TMAS) and temporal interference stimulation (TIS) to achieve such stimulations, using the characteristics of the response of brain neurons to modulated low-frequency oscillation.

Time-Ordered Recent Event (TORE) Volumes for Event Cameras.

Event cameras are an exciting, new sensor modality enabling high-speed imaging with extremely low-latency and wide dynamic range. Unfortunately, most machine learning architectures are not designed to directly handle sparse data, like that generated from event cameras. Many state-of-the-art algorithms for event cameras rely on interpolated event representations-obscuring crucial timing information, increasing the data volume, and limiting overall network performance.

Comparative Study of Transcranial Magneto-Acoustic Stimulation and Transcranial Ultrasound Stimulation of Motor Cortex.

Transcranial ultrasound stimulation (TUS; < 1 MHz) is a promising approach to non-invasive brain stimulation. Transcranial magneto-acoustic stimulation (TMAS) is a technique of neuromodulation for regulating neuroelectric-activity utilizing a magnetic-acoustic coupling electric field generated by low-intensity ultrasound and magnetic fields. However, both techniques use the physical means of low-intensity ultrasound and can induce the response of the motor cortex.