Publications by authors named "Ruixin Qin"

Bisphenols, including bisphenol A (BPA) and its analogs such as bisphenol F (BPF), bisphenol S (BPS), tetrabromobisphenol A (TBBPA), tetrachlorobisphenol A (TCBPA) and tetrabromobisphenol S (TBBPS), are typical endocrine disruptors widely used in plastic production. However, until now, the occurrence mechanisms of these bisphenols in hair, a non-invasive material for human biomonitoring, have been inadequately explored. This study employed fluorescence spectroscopy and molecular docking to investigate the interactions between these 6 bisphenols and hair keratin.

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Article Synopsis
  • Human hair is being used as a tool for monitoring exposure to organic contaminants, but external decontamination is often needed before analysis, which may affect internal contaminant levels.
  • This study investigates how different decontamination methods impact inherent organic contaminants in guinea pig hair, using six specific contaminants and various rinsing solvents.
  • Results show that the washing processes can significantly reduce the amount of these contaminants in hair, highlighting the need for careful interpretation of data regarding contaminant levels due to these decontamination effects.
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Human hair has become a promising non-invasive matrix in assessing exposure to environmental organic pollutants (OPs). However, exogenous contaminants, which were absorbed into the hair via sweat, sebum, and air particles/dust, could contribute to OP levels in hair and interfere with the precise exposure assessment. So far, the microscopic mechanisms underlying the absorption of exogenous OPs into hair remain inadequately understood.

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Vasectomized mice play a key role in the production of transgenic mice. However, vasectomy can cause great physical and psychological suffering to mice. Therefore, there is an urgent need to find a suitable replacement for vasectomized mice in the production of transgenic mice.

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Article Synopsis
  • Human hair is effective for monitoring micro-organic contaminants (MOCs), but the processes involved, especially regarding melanin's role, are not well understood.
  • A study on polycyclic aromatic hydrocarbons (PAHs) found higher concentrations in black hair compared to white hair, correlating increased melanin levels with greater PAH accumulation.
  • Both hair biomonitoring and laboratory experiments indicate that melanin significantly influences the levels of PAHs in hair, highlighting the need for consistent melanin content to ensure accurate monitoring of MOCs.
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The piRNA pathway is essential for female fertility in golden hamsters and likely humans, but not in mice. However, the role of individual PIWIs in mammalian reproduction remains poorly understood outside of mice. Here, we describe the expression profiles, subcellular localization, and knockout-associated reproductive defects for all four PIWIs in golden hamsters.

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Background: Chinese cabbage (Brassica rapa ssp. pekinensis) experienced a whole-genome triplication event and thus has three subgenomes: least fractioned, medium fractioned, and most fractioned subgenome. Environmental changes affect leaf development, which in turn influence the yield.

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Article Synopsis
  • - Indoor dust is a significant source of exposure to organophosphate flame retardants (PFRs), with urinary diester concentrations (DAPs) being used as biomarkers to assess this exposure among e-waste workers in southern China.
  • - Key findings include that Tris(1-chloro-2-propyl) phosphate (TCIPP) and triphenyl phosphate (TPHP) were the main PFRs found in dust, and significant correlations were noted between urinary DAP levels and dust concentrations, indicating both biotransformation and direct ingestion as exposure routes.
  • - BDCIPP, a metabolite of TDCIPP, emerged as a reliable biomarker due to its frequent detection in urine samples, while
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The phytochemistry investigation on the Cassia occidentalis, a Dai Medicine, was carried out. The C. occidentalis was extracted with ethanol and then partitioned with EtOAc.

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