NAC047/052/104 Synergistically Regulate the Dark-Induced Leaf Senescence in Non-Heading Chinese Cabbage.

Non-heading Chinese cabbage (NHCC) is an important vegetable, and its leaves are harvested for consumption. Thus, the initiation and progression of leaf senescence in NHCC directly impact its yield and quality. In multiple plant species, NAC transcription factors are known to act as critical regulators of leaf senescence.

Patient-surgeon racial and ethnic concordance and outcomes of older adults operated on by California licensed surgeons: an observational study.

Objective: To examine the association of patient-surgeon racial and ethnic concordance with postoperative outcomes among older adults treated by surgeons with California medical licences.

Design: Retrospective cohort study.

Setting: US acute care and critical access hospitals in 2016-2019.

Mining TCGA to reveal immunotherapy-related genes for soft tissue sarcoma.

Immunotherapy of soft tissue sarcoma is considered an important development direction for the future. Bioinformatics analysis of genetic changes in tumors and the immune microenvironment around tumors has proven to be a mature and reliable method for predicting tumor prognosis. By mining the Cancer Genome Atlas Program database, we found immunotherapy targets of soft tissue sarcoma and analyzed their biological behavior.

The formaldehyde stress on photosynthetic efficiency and oxidative stress response of moss L.

Introduction: Formaldehyde is a common gaseous pollutant emitted by buildings and decorative materials. In recent years, growing concerns have been raised regarding its harmful effects on health in indoor air. Therefore, this study aims to investigate the physiological and photosynthetic response mechanisms of under formaldehyde stress.

Potential risk of microplastics in plateau karst lakes: Insights from metagenomic analysis.

Microplastic (MP) pollution has become one of global concern. While MP pollution in lakes has been well studied, research on MP sources, distribution, and ecological risks in the Tibetan Plateau is limited. We systematically investigated the MP abundance and distribution in alpine travertine lakes in Jiuzhai nature reserve located in east edge of Qinghai-Tibetan Plateau and assessed the distributions of microbiomes, antibiotic resistance genes (ARGs), and virulence factor genes (VFGs) in water, sediments, and MPs, using macrogenomics.

The role of hypoxia/ischemia preconditioning in ischemic stroke.

Ischemic stroke can cause damage to neurons, resulting in neurological dysfunction. The main treatments in the acute phase include intravenous thrombolysis, endovascular stent-assisted vascular thrombectomy and antiplatelet therapy. Due to the limitations of the time window and the risk of early intracranial hemorrhage, finding active treatment plans is crucial for improving therapy.

Efficacy of laparoscopic cardiectomy combined with side overlap anastomosis for the treatment of terminal achalasia.

To investigate the safety and short-term effectiveness of laparoscopic-assisted cardiectomy with side-overlap esophagogastric reconstruction for the treatment of terminal or end-stage achalasia, patients with end-stage achalasia treated with laparoscopic-assisted cardiectomy with side-overlap esophagogastric reconstruction were retrospectively enrolled. The clinical data, surgical data and follow-up were analyzed. Among twenty-five patients enrolled, the achalasia type St was present in 12 (48%) patients, type Sg in 9 (36%), and type aSg in 4 (16%).

Dramatic switchable polarities in conduction type and self-driven photocurrent of BiI via pressure engineering.

The intentional manipulation of carrier characteristics serves as a fundamental principle underlying various energy-related and optoelectronic semiconductor technologies. However, achieving switchable and reversible control of the polarity within a single material to design optimized devices remains a significant challenge. Herein, we successfully achieved dramatic reversible p-n switching during the semiconductor‒semiconductor phase transition in BiI via pressure, accompanied by a substantial improvement in their photoelectric properties.

SlAN2 overexpression improves cold resistance in tomato (Solanum lycopersicum L.) by regulating glycolysis and ascorbic acid metabolism.

Chilling stress seriously affects the growth and yield of tomato. Anthocyanin is a typical chilling-induced metabolite with strong antioxidant activity and photoprotective capacity. Here, we found that anthocyanin was also involved in ascorbic acid biosynthesis and glycolysis under chilling stress.

Microcirculatory parameters as risk factors for predicting progression of posterior staphyloma in highly myopic eyes: a case-control study.

Background: To assess the rate of macular blood flow decreasing in adults with and without posterior staphyloma (PS) using optical coherence tomography angiography (OCTA) and to identify risk factors associated with PS progression.

Methods: This longitudinal case-control study enrolled 122 eyes of 122 patients-64 patients with PS (PS group) and 58 patients without PS (NPS group). Participants underwent OCTA and clinical examinations at least twice, and those followed for at least one year were included in the analysis.

Predictive factors for coronal and sagittal graft extrusion length after using tendon autograft for medial meniscus reconstruction.

Background: Meniscus extrusion occurs in most elderly individuals and most patients after meniscus allograft transplantation. The risk factors and correlative factors of meniscus extrusion have been extensively studied. However, for using tendon autograft for meniscus reconstruction, both graft type and surgical method are different from those in previous studies on meniscus extrusion.

Osteoinduction and Osteoconduction Evaluation of Biodegradable Magnesium Alloy Scaffolds in Repairing Large Segmental Defects in Long Bones of Rabbit Models.

Magnesium (Mg) alloy scaffolds demonstrate promising potential for clinical applications in the repair of segmental bone defects. However, the specific mechanisms of osteoconduction and osteoinduction facilitated by these scaffolds themselves during the bone reconstruction process remain inadequately defined. This investigation systematically assesses the properties of MAO-coated Mg base implants both in vitro and in vivo.

Discovery of potent and selective factor XIa inhibitors incorporating triazole-based benzoic acid as novel P2' fragments: Molecular dynamics simulations and anticoagulant activity.

Factor XIa (FXIa) has emerged as a novel anticoagulant target with a reduced risk of bleeding. However, due to the nearly identical residues it shares with its closest homologue, plasma kallikrein (PKa), only a few selective FXIa inhibitors have been reported. Herein, we describe the discovery of novel triazole-based pyridone derivatives as potent and selective FXIa inhibitors.

Molecule level precise construction of donor-acceptor polymeric carbon nitride for photocatalytic hydrogen evolution.

Constructing donor-acceptor structures in polymeric carbon nitride (CN) provides an attractive pathway for facilitating charge carrier separation in photocatalytic reactions. However, achieving the implantation of donor or acceptor moieties at molecule level precision remains challenging. Here we develop a three-dimensional (3D) porous thiophene implanted carbon nitride (TCN) with donor-acceptor structure via a supramolecular assembly strategy.

Real-time sub-milliwatt epilepsy detection implemented on a spiking neural network edge inference processor.

Analyzing electroencephalogram (EEG) signals to detect the epileptic seizure status of a subject presents a challenge to existing technologies aimed at providing timely and efficient diagnosis. In this study, we aimed to detect interictal and ictal periods of epileptic seizures using a spiking neural network (SNN). Our proposed approach provides an online and real-time preliminary diagnosis of epileptic seizures and helps to detect possible pathological conditions.

Electrostatically Spun Fabrication of FeO@SiO/PVA Membranes for Efficient Methyl Orange (MO) Adsorption and Response Surface Optimization of the Processes.

The environmental pollution problem caused by azo dyes urgently needs to be solved. FeO@SiO/poly(vinyl alcohol) (PVA) membranes were prepared via an electrostatic spinning process. By blending the prepared FeO@SiO nanoparticles with PVA, a uniform distribution of FeO@SiO nanoparticles within the fibers was achieved, effectively preventing the aggregation of the nanoparticles and demonstrating excellent adsorption performance toward the azo anionic dye methyl orange (MO).