Local transplantation of GMSC-derived exosomes to promote vascularized diabetic wound healing by regulating the Wnt/β-catenin pathways.

With the increasing number of diabetic patients, chronic wound healing remains a great challenge in clinical medicine. As one of the main components secreted by stem cells, the exosome is considered to be a promising candidate for promoting chronic wound healing. Here, gingival mesenchymal stem cell (GMSC)-derived exosomes (GMSC-Exo) were isolated and demonstrated to promote the proliferation, migration, and tube formation of human umbilical vein endothelial cells (HUVECs) by regulating the Wnt/β-catenin signaling pathway in a diabetic-mimicking high glucose environment.

Association of GCKR Gene Polymorphisms with Metabolic Syndrome in a Han Population from Northeast China.

Background: As a serious public universal health issue, metabolic syndrome (MetS) has a high prevalence world-wide. Some studies illustrated that GCKR modulated insulin action and serum lipids are critical diagnostic criteria of MetS. The goal of this study is to investigate the association between GCKR polymorphisms with metabolic syndrome (MetS) in a Han population from northeast China.

Stepwise clustering future meteorological drought projection and multi-level factorial analysis under climate change: A case study of the Pearl River Basin, China.

Climate change has significant impacts on the Pearl River Basin, and the regional ecological environment and human production may face severe challenges in the future due to changes in temperature and precipitation, as well as their derivative disasters (e.g., drought).

Prevalence and correlates of overweight and obesity among adolescents in northeastern China: a cross-sectional study.

Objectives: To estimate the prevalence of overweight/obesity among adolescents and evaluate the associated factors in this group in Changchun City in northeastern China.

Methods: A cross-sectional study of 1955 adolescents aged 11-18 years was conducted in Changchun City using stratified cluster sampling. Parents and caregivers of children completed the questionnaires as requested without objection.

Prevalence and correlates of poor sleep quality among college students: a cross-sectional survey.

Background: Sleep problems are widespread among college students around the globe, especially in China. This study was designed to investigate the prevalence of poor sleep quality and identify associated factors among college students in Jilin Province, China.

Methods: A total of 6284 participants were completely collected by stratified cluster sampling in 2016.

Association between ambient air pollution and pregnancy complications: A systematic review and meta-analysis of cohort studies.

Background: Pregnancy complications, such as gestational diabetes mellitus (GDM) and hypertensive disorders of pregnancy (HDP), have a great impact on public health. Exposure to ambient air pollution during pregnancy may cause pregnancy complications. The aim of our study is to explore the risk of trimester-specific maternal exposure to air pollutants on complications of pregnancy.

Comparison of Wide Margin and Inadequate Margin for Recurrence in Sacral Chordoma: A Meta-Analysis.

Study Design: .: A meta-analysis.

Objective: .

Association between RELN polymorphisms and schizophrenia in a Han population from Northeast China.

Objective: To explore the association between the RELN gene and schizophrenia in the overall sample and samples stratified by sex in a northeastern Chinese population.

Methods: A total of 1536 participants from Jilin Province, China, were recruited in this case-control study. Four single nucleotide polymorphisms (rs1062831, rs3808039, rs362746, and rs736707) in the RELN gene were genotyped.

Analysis of Factors Affecting the High Subjective Well-Being of Chinese Residents Based on the 2014 China Family Panel Study.

(1) Purpose: The purpose of our research is to understand the subjective well-being (SWB) of Chinese adult residents and its influencing factors and to identify the key groups and areas to provide a basis for the formulation of relevant policies to improve residents' happiness. (2) Methods: In this study, we analyzed the influencing factors of SWB of individuals older than 16 years of age, according to the 2014 China Family Panel Study (CFPS). We weighted 27,706 samples in the database to achieve the purpose of representing the whole country.

The diagnostic performance of PET/CT scans for the detection of para-aortic metastatic lymph nodes in patients with cervical cancer: A meta-analysis.

Objective: We performed a meta-analysis to evaluate the diagnostic value of positron emission tomography/computed tomography (PET/CT) in the detection of para-aortic lymph node metastasis in cervical cancer.

Methods: We searched the PubMed, Embase, Web of Science, Cochrane Library, Chinese Biological Medicine (CBM), Chinese National Knowledge Infrastructure (CNKI), Wanfang and VIP databases in all languages from their inception to September 2018. Stat15.

Decreased serum complement component 4 levels in patients with schizophrenia.

Dysregulation of the immune system in mental disease, particularly complement component 4 (C4), which may be associated with schizophrenia, has been repeatedly observed. This study investigated the association between the level of serum component 4 and schizophrenia. Data were derived from a case-control association study of 40 unrelated adult patients with schizophrenia and 40 matched healthy controls.