Publications by authors named "Ruirui Xuan"
Article Synopsis
- Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) have high mortality rates with limited treatment options, prompting research into human placental mesenchymal stem cells (hPMSCs) as a potential remedy.
- The study involved inducing ALI in mice using lipopolysaccharide (LPS) and administering hPMSCs, showing improved lung health and reduced inflammation through changes in key inflammatory markers.
- Findings indicated that the presence of the ACE2 gene is vital for the therapeutic effects of hPMSCs, suggesting a significant role in repairing lung tissue and providing a basis for future clinical treatments for ALI.
(1) Background: As the introduction of "positive" diagnostic criteria for metabolic dysfunction-associated fatty liver disease (MAFLD) does not exclude alcohol consumption, some patients originally diagnosed with alcoholic fatty liver disease (AFLD) may be diagnosed with dual- etiology fatty liver disease (AFLD&MAFLD), which requires us to urgently explore the impact of the changes in this classification of AFLD on clinical manifestations. (2) Methods: Utilizing data from the Nationwide Inpatient Sample database 2016-2018, a total of 9269 participants with AFLD were selected. With the definition of MAFLD, these patients were further categorized into two groups: single AFLD and AFLD&MAFLD.
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