Synopsis of recent research by authors named "Ruiqiong Ye"
- Ruiqiong Ye's research primarily focuses on understanding the molecular mechanisms of DNA double-strand break (DSB) repair, particularly the roles of long non-coding RNAs (lncRNAs) and protein kinases in this essential cellular process.
- Recent findings highlight the significant role of lncRNA LINP1 in facilitating non-homologous end joining (NHEJ) and promoting resistance to radiation and chemotherapy in cancer cells, shedding light on potential therapeutic targets.
- Ye's work also explores DNA-PKcs functions beyond traditional DSB repair, underlining its involvement in mitotic regulation and the sensitivity of ATM-deficient cancer cells to PARP inhibitors, suggesting the therapeutic potential of combining these pathways in cancer treatment.