Hubbard Gap Closure-Induced Dual-Redox Li-Storage Mechanism as the Origin of Anomalously High Capacity and Fast Ion Diffusivity in MOFs-Like Polyoxometalates.

MOFs-like polyoxometalate (POMs) electrodes, harvesting combined advantages of interlocking porosity and multi-electron transfer reaction, have already emerged as promising candidates for lithium-ion batteries (LIBs), yet the origins of the underlying redox mechanism in such materials remain a matter of uncertainty. Of critical challenges are the anomalously high storage capacities beyond their theoretical values and the fast ion diffusivity that cannot be satisfactorily comprehended in the theory of crystal lattice. Herein, for the first time we decode t electron occupation-regulated dual-redox Li-storage mechanism as the true origin of extra capacity in POMs electrodes.

Visualizing dynamic alterations of vitreous viscosity during elevated intraocular pressure in glaucoma with a Near-infrared/Magnetic resonance imaging dual-modal nanoprobe.

Glaucoma is a chronic progressive disease leading to irreversible visual impairment and blindness. High intraocular pressure (IOP) resulting from abnormally high outflow resistance is a major risk factor for glaucoma development, however, it is unclear how IOP elevation influences the structure and function of the retina and the optic nerve via vitreous humor located between the lens and retina in the eye. To understand vitreous biomechanical and stimulus response toward IOP elevation, we developed a novel near-infrared (NIR)/MRI dual-modal nanoprobe, DTA/P-NCA/17F@Co, which is composed of N, N-dimethyl-4(thien-2-yl)-aniline group (DTA) as NIR fluorophore and the fluorine-based polyamino acid cobalt nanoparticles (P-NCA/17F@Co) as T contrast agent.

Dynamic Lock-And-Release Mechanism Enables Reduced ΔG at Low Temperatures for High-Performance Polyanionic Cathode in Sodium-Ion Batteries.

Low-temperature synthesis of polyanionic cathodes for sodium-ion batteries is highly desirable but often plagued by prolonged reaction times and suboptimal crystallinity. To address these challenges, a novel self-adaptive coordination field regulation (SACFR) strategy based on a dynamic lock-and-release (DLR) mechanism is introduced. Specifically, urea is used as a DLR carrier during synthesis, which dynamically "locks" and "releases" vanadium ions for controlled release, simultaneously "locking" H ions to enhance phosphate group release, thereby creating a self-adaptive coordination field that can intelligently respond to real-time demands of the reaction system.

Burden of non-communicable diseases attributable to high temperature in a changing climate from 1990 to 2019: a global analysis.

Background: With global climate change, the health threats of ambient high temperature have received widespread attention. However, latest spatio-temporal patterns of the non-communicable diseases (NCDs) burden attributable to high temperature have not been systematically reported. We aimed to analyze vulnerable areas and populations based on a detailed profile for the NCDs burden attributable to high temperature globally.

A water-resistant, ultrathin, conformable organic photodetector for vital sign monitoring.

Ultrathin flexible photodetectors can be conformably integrated with the human body, offering promising advancements for emerging skin-interfaced sensors. However, the susceptibility to degradation in ambient and particularly in aqueous environments hinders their practical application. Here, we report a 3.

Effect of on Corrosion Behavior of X65 Carbon Steel.

X65 pipeline steel is widely used in the field of offshore oil and gas exploitation due to its excellent performance. However, due to the complex environment in the ocean, X65 pipeline steel is faced with a great risk of microbial corrosion failure. Therefore, it is of great significance to study the corrosion mechanism of X65 pipeline steel by microorganisms.

Disease burden of COPD attributable to PM in China, Japan and South Korea from 1990 to 2019: a comparative study based on Global Burden of Disease Study 2019.

Objective: We hope to reveal the changing trends of chronic obstructive pulmonary disease (COPD) burden attributable to particulate matter pollution (PM) and its age, period and cohort effects in China, Japan and Korea.

Design: We analysed the trend of COPD disease burden attributable to PM from 1990 to 2019 based on the latest Global Burden of Disease Database (GBD 2019) using JoinPoint model and analysed the effect of age, period and cohort on COPD burden attributable to PM in China, Japan and Korea from 1990 to 2019 using age-period-cohort model (model).

Setting: GBD data from 1990 to 2019.

Integrated metabolic profiling and transcriptome analysis of Lonicera japonica flowers for chlorogenic acid, luteolin and endogenous hormone syntheses.

The active ingredients of many medicinal plants are the secondary metabolites associated with the growth period. Lonicera japonica Thunb. is an important traditional Chinese medicine, and the flower development stage is an important factor that influences the quality of medicinal ingredients.

Superhydrophilicity boron-doped cobalt phosphide nanosheets decorated carbon nanotube arrays self-supported electrode for overall water splitting.

Transition metal borides (TMBs) or phosphides (TMPs) have attracted great attention to the design of bifunctional electrocatalysts for energy storage. The superaerophobicity and superhydrophilicity of the catalytic electrode surface are crucial factors to determine the reaction process of the gas electrode. Herein, we report a self-supported electrode of carbon nanotube (CNTs) array grown on carbon cloth (CC) modulated together by boron-doped cobalt phosphide (CoP-B/CNTs/CC).

Comprehensive analysis and identification of prognostic biomarkers and immunotherapeutic targets in the NADPH oxidase family (and its regulatory subunits) in pancreatic ductal adenocarcinoma.

Purpose: This study aimed to evaluate the role of NADPH in pancreatic ductal adenocarcinoma using bioinformatic analyses and experimental validations.

Methods: We compared the expression levels, performed GO and KEGG analysis of NADPH oxidase family and its regulatory subunits, and determined the survival of patients with pancreatic ductal adenocarcinoma by GEPIA, David and KM plotter. The relationship between their expression with immune infiltration levels, phagocytotic/NK cell immune checkpoints, recruitment-related molecules were detected by Timer 2.

Effect of on corrosion of X65 pipeline steel.

Microbiologically influenced corrosion (MIC) has caused great losses to many industries. This paper aimed to study the corrosion behavior of on X65 steel. The corrosion behavior of on X65 steel under aerobic and anaerobic conditions was studied by scanning electron microscopy, energy dispersive spectrometer and electrochemical analysis techniques.

Efficient passively Q switched lasers with a large-energy stored Yb:LuScO crystal.

Ytterbium (Yb)-ions-doped sesquioxide crystal is an attractive gain medium for a tunable and pulsed laser owing to its high thermal conductivity. In particular, it has been identified that Yb:LuScO has the largest energy storage property compared with other sesquioxide crystals, which is favorable for passive Q switching. In this Letter, continuous wave (CW) and the first, to the best of our knowledge, passively Q switched laser operations were demonstrated with a Yb:LuScO crystal.

CoP/CoP Encapsulated in Carbon Nanotube Arrays to Construct Self-Supported Electrodes for Overall Electrochemical Water Splitting.

Electrocatalytic water splitting is a desirable and sustainable strategy for hydrogen production yet still faces challenges due to the sluggish kinetics and rapid deactivation of catalysts in the oxygen evolution process. Herein, we utilized the metal-catalyzed growth technology and phosphating process to fabricate self-supported electrodes (CoP@CNT-CC) composed of carbon nanotube (CNT) arrays grown on carbon cloth (CC); thereinto, cobalt-based phosphide nanoparticles (CoP) are uniformly encapsulated in the cavity of the CNTs. After further optimization, when the nanoparticles are in the composite phase (CoP/CoP), CoP/CoP@CNT-CC served as catalytic electrodes with the highest activity and stability for electrocatalytic water splitting in an alkaline medium (1.

Investigation of crystal field effects for the spectral broadening of Yb-doped Lu Y O sesquioxide crystals.

The investigation of crystal field effects is significant for elucidating the spectral characteristics of Yb-doped sesquioxide crystals for ultrafast laser generation. The narrow spectra of Yb-doped single sesquioxide crystals limit the generation of ultrafast lasers; in this study, the Y ions were introduced into LuO single crystals by the employment of ion replacement to broaden the spectra. To analyze the spectral broadening, the responsible crystal field parameters (CFPs) were calculated.

Deep learning for non-parameterized MEMS structural design.

The geometric designs of MEMS devices can profoundly impact their physical properties and eventual performances. However, it is challenging for researchers to rationally consider a large number of possible designs, as it would be very time- and resource-consuming to study all these cases using numerical simulation. In this paper, we report the use of deep learning techniques to accelerate the MEMS design cycle by quickly and accurately predicting the physical properties of numerous design candidates with vastly different geometric features.

Anti-inflammatory effects of Platycodin D on dextran sulfate sodium (DSS) induced colitis and E. coli Lipopolysaccharide (LPS) induced inflammation.

Platycodin D (PLD) is a saponin found in Platycodon grandiflorum, which has been reported to have anti-inflammatory effects. However, the effects of PLD on ulcerative colitis (UC) remain unknown. In this study, PLD showed the potential to reduce inflammation, ameliorate intestinal damage, and maintain intestinal integrity in DSS-induced colitis.

Gradient-Band Alignment Homojunction Perovskite Quantum Dot Solar Cells.

The inorganic perovskite CsPbI that exists in the form of a quantum dot (QD) shows a stable cubic structure, attracting much attention for its application in solar cells. However, too many grain boundaries in the perovskite QD (PQD) layer block the transport of carriers, resulting in the potential loss of solar cells. Herein, we devise a gradient-band alignment (GBA) homojunction, which is constructed from three layers of PQDs with different band-gaps to form a gradient energy alignment.

Spray Coated Colloidal Quantum Dot Films for Broadband Photodetectors.

A technique for scalable spray coating of colloidal CdSeTe quantum dots (QDs) for photovoltaics and photodetector applications is presented. A mixture solvent with water and ethanol was introduced to enhance the adhesive force between QDs and the substrate interface. The performance of the detector reached the highest values with 40 spray coating cycles of QD deposition.

Synthesis of Colloidal Blue-Emitting InP/ZnS Core/Shell Quantum Dots with the Assistance of Copper Cations.

Colloidal InP quantum dots (QDs) have been considered as one of the most promising candidates for display and biolabeling applications because they are intrinsically toxicity-free and exhibit high photoluminescence. On account of the uncontrollable nucleation and growth during the synthesis of InP, obtaining high-quality blue-emitting InP QDs with uniform size distribution remains a challenge. Herein, we employ a novel synthetic approach for producing blue-emitting InP/ZnS core/shell QDs with the assistance of copper cations.

CuInSe Quantum Dots Hybrid Hole Transfer Layer for Halide Perovskite Photodetectors.

A novel hybrid hole transport layer (HTL) of CuInSe quantum dots (QDs)/poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) was developed to enhance the performance of halide metal perovskite (MAPbI)-based photodetectors. The introduction of CuInSe QDs not only improved the wettability of the PEDOT:PSS HTL for the growth of perovskite crystals but also facilitated the transportation of holes from the perovskite to the HTL. As a result, both responsivity and detectivity of the device were increased dramatically by CuInSe QDs hybrid HTL, showing excellent photoresponsivity of 240 mA/W, larger ratio of photocurrent density to dark current density of 4.

Percutaneous trans-apex intra-septal radiofrequency ablation of hypertrophic cardiomyopathy.

A 70-year-old woman presented with severe hypertrophic obstructive cardiomyopathy (HOCM) (maximum ventricular septum thickness of 28 mm, peak pressure gradient (PG) in the left ventricular outflow tract (LVOT) of 153 mmHg). We performed percutaneous trans-apex intra-septal radiofrequency ablation (PTAISRA) of the interventricular septum under guidance of transthoracic echocardiography. At six-months follow up, the symptoms were significantly relieved; the septal thickness was reduced to 18 mm and the peak LVOT PG reduced to 44 mmHg.

The Cumulative Effects of the MYH7-V878A and CACNA1C-A1594V Mutations in a Chinese Family with Hypertrophic Cardiomyopathy.

Aims: We investigated the pathogenesis of MYH7-V878A and CACNA1C-A1594V mutations in a Chinese family with hypertrophic cardiomyopathy.

Methods: Clinical, electrocardiographic (ECG), echocardiographic, and cardiac magnetic resonance (CMR) examinations of members of a Chinese family were followed by exon and boarding intron analyses of 96 genes in the proband using second-generation sequencing. We confirmed the mutations by bidirectional Sanger sequencing in the members and in 300 healthy controls.

[Analysis of genotype and phenotype correlation of MYH7-V878A mutation among ethnic Han Chinese pedigrees affected with hypertrophic cardiomyopathy].

Objective: To analyze the phenotype-genotype correlation of MYH7-V878A mutation.

Methods: Exonic amplification and high-throughput sequencing of 96-cardiovascular disease-related genes were carried out on probands from 210 pedigrees affected with hypertrophic cardiomyopathy (HCM). For the probands, their family members, and 300 healthy volunteers, the identified MYH7-V878A mutation was verified by Sanger sequencing.

SbHKT1;4, a member of the high-affinity potassium transporter gene family from Sorghum bicolor, functions to maintain optimal Na⁺ /K⁺ balance under Na⁺ stress.

In halophytic plants, the high-affinity potassium transporter HKT gene family can selectively uptake K⁺ in the presence of toxic concentrations of Na⁺. This has so far not been well examined in glycophytic crops. Here, we report the characterization of SbHKT1;4, a member of the HKT gene family from Sorghum bicolor.