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Publications by authors named "Ruilin Tian"

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Synopsis of recent research by authors named "Ruilin Tian"

  • - Ruilin Tian's research focuses on innovative strategies for targeted protein degradation using PROTAC technology, specifically developing alkenyl oxindole warheads to target E3 ligases like DCAF11 for BRD4 inhibition, highlighting advancements in molecular design and high-throughput screening methodologies.
  • - The author has also investigated mechanisms of ferroptosis in liver cancer, identifying that Temsirolimus can inhibit the FSP1 enzyme to induce cell death, offering potential therapeutic avenues against chemoresistant tumor cells.
  • - Additionally, Ruilin Tian explores complex genomic and cellular dynamics, including the role of noncoding RNAs and CRISPR-based genetic screening in glioblastoma, as well as organism-specific studies on the effects of temperature on pest species, which collectively contribute to understanding cancer treatment and agricultural challenges.

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