Endoscopic cartilage underlay myringoplasty with or without balloon Eustachian tuboplasty for chronic perforation with Eustachian tube dysfunction.

Objective: The objective of this study was to compare the outcomes of endoscopic cartilage underlay myringoplasty(CNM) with or without balloon Eustachian tuboplasty (BET) for the treatment of chronic perforation with Eustachian tube dysfunction (ETD).

Materials And Methods: A total of 50 ears diagnosed with chronic perforation and ETD were randomly divided into receiving alone CNM and CNM + BET. During the 12 months follow-up, the Eustachian tube score (ETS), Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7), ET inflammation scale, hearing results and graft success rate of the patients were recorded and analyzed.

Study on the influence of coal fire on the temporal and spatial distribution of CO and CH gas emissions.

In order to study the impact of gas released from coal fire combustion on the spatial-temporal distribution of CO and CH and other greenhouse gas emissions, the impact of regional coal fire on CO and CH emission flux was comprehensively evaluated using Landsat 8 and GOSAT satellite data in Xinjiang. In addition, typical fire areas are selected, a single-channel algorithm is used to invert the surface temperature of the coal field, the spatial distribution of the coal fire area is extracted by setting the threshold, and the influence law of CO and CH emissions in the typical fire area is accurately analyzed. The results show that during 2017-2018, CO and CH emissions in Xinjiang were generally dispersed and locally concentrated, while CO-O and CH-O were at low levels in most regions, fluctuating in the ranges of 0.

Correlation between pure tone audiometry at all frequencies and distortion product otoacoustic emission of patients with hidden hearing loss.

To explore the correlation between pure tone audiometry at all frequencies and distortion product otoacoustic emission (DPOAE) of hidden hearing loss (HHL). The workers exposed to noise from a factory in Zhangjiakou (noise exposure group,  = 73) and normal young and middle-aged people recruited by society (control group,  = 77) from August 2021 to April 2022 were study subjects, and all of them underwent audiometry in clinic. Compared with the control group, the noise exposure group had significantly higher threshold by extended high-frequency audiometry at all frequencies and higher signal-to-noise ratio threshold (SNR50) (all  < 0.

Research on Evaluation of University Emergency Management Ability Based on BP Neural Network.

University emergency management ability is an important part of university safety management. To evaluate university emergency management ability scientifically, objectively, and accurately, this study constructs three first-level indexes, namely, pre-prevention ability, in-process control ability, and post-recovery ability, and 15 s-level indexes, including the establishment of emergency management institutions; the construction of emergency plans; the allocation of emergency personnel, equipment, and materials; and the training and exercise of emergency plans. On the basis of the backpropagation (BP) neural network method and MATLAB platform, an evaluation model of university emergency management ability is constructed.

Comprehensive Evaluation of University Safety Culture Construction Level Based on "2-4" Model.

Based on the "2-4" model of accident causation, a comprehensive index system of the safety culture construction level in colleges and universities is set up. This system consists of 4 primary indicators and 28 secondary indicators. Taking a university as an example, applying the analytic hierarchy process and fuzzy comprehensive evaluation method, this study establishes a comprehensive evaluation model to evaluate the construction level of the university's safety culture.

MicroRNA-130a regulated by HPV18 E6 promotes proliferation and invasion of cervical cancer cells by targeting TIMP2.

[This retracts the article DOI: 10.3892/etm.2019.

[Diagnostic value of multi-slice spiral CT in tympanic wall destruction of middle ear cholesteatoma].

To investigate the correlation between preoperative temporal bone Computed Tomography （CT） findings and intraoperative manifestations in patients with middle ear cholesteatoma. The patients with cholesteatoma undergoing surgery in our hospital from March 2017 to November 2020 were retrospectively analyzed.The temporal bone CT findings of tympanoid wall status before operation and the state of tympanic wall during operation were compared.

[Retracted] miR‑22 inhibits proliferation and invasion in estrogen receptor α‑positive endometrial endometrioid carcinomas cells.

Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the cell‑cycle data shown in Fig. 4A and Transwell cell migration data shown in Fig. 5A were strikingly similar to data appearing in different form in other articles by different authors.

Establishment of a porcine parvovirus (PPV) LAMP visual rapid detection method.

Porcine parvovirus (PPV) is one of the major causes of reproductive pig disease. Due to its serious nature, wide spread and consequent great damage to the swine industry, an effective, rapid and convenient method for its detection is needed. A loop-mediated isothermal amplification (LAMP) assay was established to detect PPV infection.

MicroRNA-130a regulated by HPV18 E6 promotes proliferation and invasion of cervical cancer cells by targeting TIMP2.

Human papillomaviruses (HPVs) have important roles in the development and progression of cervical cancer, but the underlying mechanisms are yet to be fully elucidated. MicroRNA-130a (miR-130a) has previously been reported to promote cervical cancer growth. However, the underlying molecular mechanisms by which miR-130a promotes cervical cancer progression have remained largely elusive.

A novel emulsion PCR method coupled with fluorescence spectrophotometry for simultaneous qualitative, quantitative and high-throughput detection of multiple DNA targets.

We constructed and validated a novel emulsion PCR method combined with fluorescence spectrophotometry (EPFS) for simultaneous qualitative, quantitative and high-throughput detection of multiple DNA targets. In a single reaction set, each pair of primers was labeled with a specific fluorophore. Through emulsion PCR, a target DNA was amplified in droplets that functioned as micro-reactors.

Dietary safety assessment of genetically modified rice EH rich in β-carotene.

This 90-day study aimed to assess the dietary safety of transgenic rice EH which is rich in β-carotene. Two experimental groups of Sprague-Dawley rats were fed diets containing 45% rice flour of Zhonghua 11 rice and transgenic rice EH rich in β-carotene, respectively. The reference group was fed a diet containing standard feed nutrition.

miR-22 inhibits proliferation and invasion in estrogen receptor α-positive endometrial endometrioid carcinomas cells.

Endometrial endometrioid carcinomas (EECs) account for >80% of endometrial carcinomas (ECs). Continuous stimulation of the endometrium by estrogen is a risk factor for the tumorigenesis of estrogen receptor (ER) α-positive EEC. MicroRNA-22 (miR-22) has been reported to be implicated in the regulation of various types of cancer and directly targets ERα.

HPV16E7 silencing enhances susceptibility of CaSki cells to natural killer cells.

The aim of the present study was to investigate the cytotoxicity of natural killer (NK) cells to CaSki cells following knockdown of the E7 protein of the human papillomavirus type 16 (HPV16E7). Recombinant adenovirus-short hairpin-E7 protein of the human panillomavirus type 16 (Ad‑sh‑HPV16E7) was constructed and used to infect CaSki cells. The expression of HPV16E7 in CaSki cells was assessed using western blot analysis.

The mTOR inhibitor AZD8055 inhibits proliferation and glycolysis in cervical cancer cells.

The aim of the present study was to determine the effect of AZD8055 on proliferation, apoptosis and glycolysis in the human cervical cancer cell line HeLa and to investigate the underlying mechanism(s) of action. HeLa human cervical cancer cells were treated with 10 nM AZD8055 for 24, 48 or 72 h. MTT was used to determine cell proliferation.