Conditional Knockout Reveals Crucial Involvement in Development and Function of Kidney Collecting Ducts.

Lysine-specific histone demethylase 2 () is essential for histone modifications involved in development and associated diseases. Nevertheless, the specific functions of in renal development and pathology remain largely unexplored. This study aimed to elucidate the roles of in sustaining the biological functions of the kidney by generating mutant mice with deletion using the -cre/Loxp system.