A thermo-mechanical coupling load model for high-frequency piezoelectric ultrasonic transducer.

The ultrasonic micromachining systems significantly improve machining efficiency and quality, which are increasingly being applied in the manufacturing of microstructures and micro parts. However, the mechanical and thermal loads of the high-frequency piezoelectric ultrasonic transducer (HPUT) of ultrasonic micromachining systems have serious interference with the precise control of resonance frequency tracking, which further causes uncontrollable processing quality and precision. To improve the controllability of resonance frequency tracking, a thermo-mechanical coupling load model for HPUTs is proposed to establish the relationship between the resonance frequency and thermo-mechanical coupling load by introducing the force load constants and thermal load constants into the 6-terminal network electromechanical equivalent circuit.

Protocol for preparing mammalian skin samples encompassing hair follicles for spatial transcriptomics.

Spatial transcriptomics enables a single-cell resolution view of gene expression patterns in tissues, providing insight into their biological functions. However, applying this approach to the skin presents inherent challenges. Here, we present a protocol for preparing mammalian skin samples encompassing hair follicles for spatial transcriptomics.

Angular-dependent magnetoresistance modulated by interfacial magnetic state in Pt/LSMO heterostructures.

The interfaces between heavy metals and antiferromagnetic materials have garnered significant attention due to their interesting physical properties. LaSrMnO (LSMO), as a typical manganite, exhibits an antiferromagnetic ground state that can be controlled through epitaxial strain and interfacial spin-orbit coupling. In this work, we reported the diverse magnetoresistance, influenced by the interfacial magnetic state, in Pt (3 nm)/LSMO (6-20 nm) heterostructures.

Exhaust and evaporative volatile organic compounds emissions from vehicles fueled with ethanol-blended-gasoline.

By 2020, China has implemented the use of 10% ethanol-blended-gasoline (E10), which is expected to notably impact vehicular volatile organic compounds (VOCs) emissions. The adoption of E10 reduced certain emissions but raised concerns with about more reactive oxygenated volatile organic compounds (OVOCs). This study aimed to evaluate the impact of E10 on the total VOCs emissions from both exhaust and evaporative emissions by conducting tests on the CHINA V (or CHINA VI) light-duty gasoline vehicles (LDGVs) using 0% ethanol blended gasoline (E0) and E10.

The Impact of Atmospheric Cadmium Exposure on Colon Cancer and the Invasiveness of Intestinal Stents in the Cancerous Colon.

Background: Inhalation exposure to carcinogenic metals such as cadmium (Cd) is a significant global health concern linked to various cancers. However, the precise carcinogenic mechanism underlying inhalation exposure remains elusive.

Methods: In this study, CT26 mouse colon cancer (CC) cells were implanted into BALB/c mice to establish CC mouse models.

Insights into the mechanism of transcription factors in Pb-induced apoptosis.

The health risks associated with exposure to heavy metals, such as Pb, are increasingly concerning the public. Pb can cause significant harm to the human body through oxidative stress, autophagy, inflammation, and DNA damage, disrupting cellular homeostasis and ultimately leading to cell death. Among these mechanisms, apoptosis is considered crucial.

Dark2Light: multi-stage progressive learning model for low-light image enhancement.

Due to severe noise and extremely low illuminance, restoring from low-light images to normal-light images remains challenging. Unpredictable noise can tangle the weak signals, making it difficult for models to learn signals from low-light images, while simply restoring the illumination can lead to noise amplification. To address this dilemma, we propose a multi-stage model that can progressively restore normal-light images from low-light images, namely Dark2Light.

Effect of N and CO on the Explosion Properties of High Equivalence Ratios of Hydrogen.

The explosion characteristics of premixed gases under different equivalence ratios (1.0-3.0) and inert gas addition (5-20%) are experimentally investigated, and sensitivity analysis of the radical reactions is carried out using the USC Mech II model to analyze the molar fraction of radicals.

Evaluating vehicular exhaust and evaporative emissions via VOC measurement in an underground parking garage.

Vehicular emissions, including both tailpipe exhaust and evaporative emissions, are major anthropogenic sources of volatile organic compounds (VOCs) in urban cities. Current knowledge on vehicle tailpipe and evaporative emissions was mainly obtained via laboratory tests on very few vehicles under experimental conditions. Information on fleet gasoline vehicles emission features under real-world conditions is lacking.

SCYN: single cell CNV profiling method using dynamic programming.

Background: Copy number variation is crucial in deciphering the mechanism and cure of complex disorders and cancers. The recent advancement of scDNA sequencing technology sheds light upon addressing intratumor heterogeneity, detecting rare subclones, and reconstructing tumor evolution lineages at single-cell resolution. Nevertheless, the current circular binary segmentation based approach proves to fail to efficiently and effectively identify copy number shifts on some exceptional trails.

Somatic variant analysis suite: copy number variation clonal visualization online platform for large-scale single-cell genomics.

The recent advance of single-cell copy number variation (CNV) analysis plays an essential role in addressing intratumor heterogeneity, identifying tumor subgroups and restoring tumor-evolving trajectories at single-cell scale. Informative visualization of copy number analysis results boosts productive scientific exploration, validation and sharing. Several single-cell analysis figures have the effectiveness of visualizations for understanding single-cell genomics in published articles and software packages.

Landscape change patterns at three stages of the construction and operation of the TGP.

Analyses of landscape change patterns that are based on elevation and slope can not only provide reasonable interpretations of landscape patterns but can also help to reveal evolutionary laws. However, landscape change patterns and their model in different landforms of the typical watershed in the Three Gorges Reservoir Area (TGRA) has not been quantified and assessed effectively. As a complex geographical unit, the ecological environment in the middle reach of the Yangtze River has experienced great changes due to the construction of the Three Gorges Project (TGP) and its associated human activities.

Effect of Inert Gas CO on Deflagration Pressure of CH/CO.

To study the effect of CO on the explosion characteristics of CH/CO, the explosion experiments of the effect of different volume fractions of CO on CH/CO deflagration were carried out by using the self-developed pipeline gas explosion experimental platform. The explosion characteristics of premixed gas are studied from the aspects of explosion peak pressure and time of reaching the peak pressure. The results show that the effect of CO on the deflagration of methane with a different volume fraction is the result of the interaction of the elementary reaction and the oxygen content in the reaction system.