Fine-tuning bromide AIE probes for Hg detection in mitochondria with wash-free staining.

Mercury ions (Hg) primarily target mitochondria in the cells. Therefore, the development of novel probes that specifically target mitochondria in the presence of Hg is of immense importance. Most previously reported probes that utilize the softness of S, Te, O, and/or N atoms for Hg binding often face problems such as fluorescence quenching and off-target signals.

A Theoretical Study on the Degradation Mechanism, Kinetics, and Ecotoxicity of Metronidazole (MNZ) in •OH- and SO-Assisted Advanced Oxidation Processes.

Metronidazole (MNZ), a typical example of nitroimidazole antibiotics, is widely used in the treatment of infectious diseases caused by anaerobic bacteria. The degradation mechanism and kinetics of MNZ in the presence of HO• and SO were studied using density functional theory (DFT). It was confirmed that both HO• and SO easily added to the carbon atom bonded to the NO group in the MNZ molecule as the most feasible reaction channel.