Double-target Magnetic Stimulation Attenuates Oligodendrocyte Apoptosis and Oxidative Stress Impairment after Spinal Cord Injury via GAP43.

Background Context: Spinal cord injury (SCI) causes neural circuit interruption and permanent functional damage. Magnetic stimulation in humans with SCI aims to engage residual neural networks to improve neurological functional, but the detailed mechanism remains unknown.

Purpose: This study evaluates functional recovery and neural circuitry improvements in rodent with double-target (brain and spinal cord) magnetic stimulation (DTMS) treatment and explores the effect of DTMS on the modulation of glial cells in vivo and in vitro.

The association of combined vitamin C and D deficiency with bone mineral density and vertebral fracture.

Purpose: Both vitamin C and D deficiencies are extremely common in clinical practice, especially in elderly population. Unfortunately, the role of vitamin C deficiency in osteoporosis related consequences is often neglected. The aim of the present study is to analyse if combined vitamin C and D deficiency would have an association with bone mineral density (BMD) and osteoporotic vertebral fracture (OVF).

Prenatal diagnosis of dent disease type I with a nonsense pathogenic variant in CLCN5: a case study.

Introduction: Dent disease type I is a rare X-linked recessive renal tubular disease resulting from pathogenic variants in the CLCN5 gene. Due to the rarity of Dent disease type I and the diversity of its phenotypes, its clinical diagnosis is complex and poses a challenge to clinicians.

Methods: A foetus and a child from a 36-year-old pregnant woman with a birth history of abnormal children were enrolled in this study.

Accuracy of cytokeratin 19 fragment in the diagnosis of bladder cancer.

CYFRA21-1 is a biomarker of cancer and has a promising future in the diagnosis of bladder cancer. The purpose of this study was to assess the diagnostic accuracy of CYFRA21-1 for bladder cancer. We included articles from the Cochrane Library, Web of Science, PubMed and Embase.