Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2.

Atherosclerosis is a chronic inflammatory disease implicated in oxidative stress and endothelial dysfunction. Protein disulfide-isomerase A3 (PDIA3) has been reported to regulate oxidative stress and suppress inflammation. This study aimed to explore the function of PDIA3 in atherosclerosis and the underlying mechanisms.

In vitro Dynamic Pharmacokinetic/Pharmacodynamic (PK/PD) study and COPD of Marbofloxacin against Haemophilus parasuis.

Background: Haemophilus parasuis (H. parasuis) can invade the body and cause systemic infection under stress conditions. Marbofloxacin has been recommended for the treatment of swine infections.

In vitro dynamic pharmacokinetic/pharmacodynamic(PK/PD) modeling and PK/PD cutoff of cefquinome against Haemophilus parasuis.

Background: Haemophilus parasuis (H. parasuis) causes Glässer's disease and multisystem infectious disease. It is one of the major causes of nursery mortality in swine herds.

[Diagnosis boundary values of metabolic syndrome obesity index for children and adolescents].

Objective: To determine the distribution characteristics of waist circumference (WC), waist height ratio (WHtR) of 6-18 years olds in Guangzhou, and to put forward the WC and WHtR appropriate boundary values for 6-18 years olds on the basis of cardiovascular disease (CVD) risk factor assessment.

Methods: We analyzed the height, weight, WC and its metabolic indication data (blood pressure, fasting blood glucose, and blood lipids) of 15 000 children in Guangzhou, aged 6-18, with the receiver-operating characteristic curve (ROC), and explored the best value point of WC and WHtR for the prediction of cardiovascular diseases.

Results: When the WC percent reached P85, and WHtR reached 0.

[Determination of residual monomers in polymer water treatment chemicals using high performance liquid chromatography].

A method was developed for the determination of residual monomers in polymer water treatment chemicals (sodium of polyepoxysuccinic acid (PESA), acrylic acid/maleic anhydride copolymer (AA/MA), polyacrylic acid (PAA), sodium of hydrolyzed polymaleic acid (HPMA), and maleic anhydride/acrylic acid/methyl acrylate copolymer (MA/AA/MAc) using high performance liquid chromatography. The separation was performed on a ZORBAX 300SB-C18 column (5 microm, 150 mm x 4.6 mm).