Paradigms and methods of noninvasive brain-computer interfaces in motor or communication assistance and rehabilitation: a systematic review.

Noninvasive brain-computer interfaces (BCIs) have rapidly developed over the past decade. This new technology utilizes magneto-electrical recording or hemodynamic imaging approaches to acquire neurophysiological signals noninvasively, such as electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS). These noninvasive signals have different temporal resolutions ranging from milliseconds to seconds and various spatial resolutions ranging from centimeters to millimeters.

Improving Reliability of Life Applications Using Model-based Brain Switches via SSVEP.

The brain switch improves the reliability of asynchronous brain-computer interface (aBCI) systems by switching the control state of the BCI system. Traditional brain switch research focuses on extracting advanced electroencephalography (EEG) features. However, a low signal-to-noise ratio (SNR) of EEG signals resulted in limited feature information and low performance of brain switches.

Compensating K Ions Through an Organic Salt in Electrolytes for Practical K-Ion Batteries.

K-ion batteries face significant challenges due to a severe shortage of active K ions, with cathode materials typically containing less than 70% K ions and first-cycle irreversible reactions consuming up to 20% more. Conventional K-ion compensation methods fail to supply sufficient K ions without compromising cell integrity. To address this, we introduce potassium sulfocyanate (KSCN) as an electrolyte additive capable of delivering up to 100% active K ions.

Coupling active and inactive transition metals to boost calcium storage cycle stability for Prussian blue cathodes.

Due to the advantages of resource abundance and low reduction potential of calcium, calcium-ion battery (CIB) becomes one of the potential candidates for energy storage devices. Prussian blue analogues (PBAs) are promising cathode materials for CIB, but they suffer from limited capacity and poor cyclability. Herein, a new PBA cathode NiCoHCF is designed with electrochemical active Co and inactive Ni.

Action Observation With Rhythm Imagery (AORI): A Novel Paradigm to Activate Motor-Related Pattern for High-Performance Motor Decoding.

Objective: The Motor Imagery (MI) paradigm has been widely used in brain-computer interface (BCI) for device control and motor rehabilitation. However, the MI paradigm faces challenges such as comprehension difficulty and limited decoding accuracy. Therefore, we propose the Action Observation with Rhythm Imagery (AORI) as a natural paradigm to provide distinct features for high-performance decoding.

Tudor-SN exacerbates pathological vascular remodeling by promoting the polyubiquitination of PTEN via NEDD4-1.

Background: Dysregulation of vascular homeostasis can induce cardiovascular diseases and increase global mortality rates. Although lineage tracing studies have confirmed the pivotal role of modulated vascular smooth muscle cells (VSMCs) in the progression of pathological vascular remodeling, the underlying mechanisms are still unclear.

Methods: The expression of Tudor-SN was determined in VSMCs of artery stenosis, PDGF-BB-treated VSMCs and atherosclerotic plaque.

A model-based brain switch via periodic motor imagery modulation for asynchronous brain-computer interfaces.

Brain switches provide a tangible solution to asynchronized brain-computer interface, which decodes user intention without a pre-programmed structure. However, most brain switches based on electroencephalography signals have high false positive rates (FPRs), resulting in less practicality. This research aims to improve the operating mode and usability of the brain switch.

Effect of motion state variability on error-related potentials during continuous feedback paradigms and their consequences for classification.

Background: An erroneous motion would elicit the error-related potential (ErrP) when humans monitor the behavior of the external devices. This EEG modality has been largely applied to brain-computer interface in an active or passive manner with discrete visual feedback. However, the effect of variable motion state on ErrP morphology and classification performance raises concerns when the interaction is conducted with continuous visual feedback.

Decoding movement frequencies and limbs based on steady-state movement-related rhythms from noninvasive EEG.

Decoding different types of movements noninvasively from electroencephalography (EEG) is an essential topic in neural engineering, especially in brain-computer interface. Although the widely used sensorimotor rhythm (SMR) is efficient in limb decoding, it lacks efficacy in decoding movement frequencies. Accumulating evidence supports the notion that the movement frequency is encoded in the steady-state movement-related rhythm (SSMRR).

Tetrahedral Occupied V Ions Enabling Reversible Three-Electron Redox of Cr /Cr in Layered Cathode Materials for Potassium-Ion Batteries.

Reversible three-electron redox of Cr /Cr in layered cathode materials for rechargeable batteries is very attractive in layered cathode materials, which leads to high capacity and energy density for rechargeable batteries. However, the poor reversibility and Cr-ion migration make it very challenging. In this work, by introducing V ions into tetrahedral sites of layer-structured NaCrO , reversible three-electron redox of Cr /Cr is realized successfully in NaCr V O (NCV05) cathode for potassium-ion batteries with a cut-off voltage of 4.

CircRNA circ-MYBL2 absorbs precursor miR-92b in the nucleus to suppress its role in enhancing gastric cancer cell proliferation.

Background: MM-associated circular RNA (Circ-MYBL2), a circular RNA (circRNA), participates in cancer biology. However, its role in gastric cancer (GC) is unclear. In this study, circ-MYBL2 was predicted to interact with precursor microRNA-92b (miR-92b).

ADAR1 inhibits adipogenesis and obesity by interacting with Dicer to promote the maturation of miR-155-5P.

Adipogenesis is closely related to various metabolic diseases, such as obesity, type 2 diabetes, cardiovascular diseases and cancer. This cellular process is highly dependent on the expression and sequential activation of a diverse group of transcription factors. Here, we report that ADAR1 (also known as ADAR) could inhibit adipogenesis through binding with Dicer (also known as DICER1), resulting in enhanced production of miR-155-5p, which downregulates the adipogenic early transcription factor C/EBPβ.

A Tenofovir-Loaded Glycyrrhetinic Acid-Modified Cationic Liposome for Targeted Therapy of Hepatitis B Virus.

Tenofovir (TFV), an acyclic nucleoside analog, exhibits potent anti-HBV activity. However, poor bioavailability, nephrotoxicity and bone toxicity limit its further clinical application. In this work, a novel tenofovir-loaded glycyrrhetinic acidmodified cationic liposome (TGCL) was prepared for targeted therapy of HBV.

Is MicroRNA-127 a Novel Biomarker for Acute Pancreatitis with Lung Injury?

Background And Aims: The aim of this study was to determine the expression of microRNA-127 (miR-127) in both rat models and patients of acute pancreatitis (AP) with lung injury (LI).

Methods: Rats were administrated with retrograde cholangiopancreatography injection of 0.5% or 3.

In-service crosstalk monitoring, tracing and lightpath re-optimization for space-division multiplexing optical networks.

In recent years, to enlarge the single-mode fibers (SMFs) transmission capacity, researchers focused on the dimension of space, which is a new degree of freedom that is being considered for optical fiber communication beyond WDM. Space-division multiplexing (SDM), including mode-division multiplexing (MDM) using multimode fibers (MMFs) or few-mode fibers (FMFs), and core multiplexing using multicore fibers (MCFs), has attracted much recent attention. In an SDM system, high-density spatial channels are tightly packed into a single fiber, thus making crosstalk among cores or modes a critical challenge due to fiber imperfections, bending, and twisting.

Chai-Qin-Cheng-Qi Decoction and Carbachol Improve Intestinal Motility by Regulating Protein Kinase C-Mediated Ca Release in Colonic Smooth Muscle Cells in Rats with Acute Necrotising Pancreatitis.

Chai-Qin-Cheng-Qi decoction (CQCQD) improves intestinal motility in acute pancreatitis (AP), but the mechanism(s) require elucidation. We investigated the effects of CQCQD and carbachol, a prokinetic agent, on colonic smooth muscle cells (SMCs) in L-arginine-induced necrotising AP model in rats. In treatment groups, intragastric CQCQD (20 g/kg, 2 hourly × 3 doses) or intraperitoneal carbachol (60 g/kg) was given 24 hours after induction of AP.

Key Molecular Mechanisms of Chaiqinchengqi Decoction in Alleviating the Pulmonary Albumin Leakage Caused by Endotoxemia in Severe Acute Pancreatitis Rats.

To reveal the key molecular mechanisms of Chaiqinchengqi decoction (CQCQD) in alleviating the pulmonary albumin leakage caused by endotoxemia in severe acute pancreatitis (SAP) rats. Rats models of SAP endotoxemia-induced acute lung injury were established, the studies in vivo provided the important evidences that the therapy of CQCQD significantly ameliorated the increases in plasma levels of lipopolysaccharide (LPS), sCd14, and Lbp, the elevation of serum amylase level, the enhancements of systemic and pulmonary albumin leakage, and the depravation of airways indicators, thus improving respiratory dysfunction and also pancreatic and pulmonary histopathological changes. According to the analyses of rats pulmonary tissue microarray and protein-protein interaction network, c-Fos, c-Src, and p85α were predicted as the target proteins for CQCQD in alleviating pulmonary albumin leakage.

Effect of Chaiqinchengqi decoction on inositol requiring enzyme 1α in alveolar macrophages of dogs with acute necrotising pancreatitis induced by sodium taurocholate.

Objective: To investigate the effect of Chaiqinchengqi decoction (CQCQD) on inositol requiring enzyme lα (IRElα) in alveolar macrophages (AMs) of the dog model of acute necrotising pancreatitis (ANP) induced by sodium taurocholate.

Methods: Fifteen beagle dogs were randomised into a control group, ANP group and CQCQD group (n = 5 per group). ANP was induced by a retrograde duct injection of 50 mg/kg of 5% sodium taurocholate.

In vitro Study of the Antagonistic Effect of Low-dose Liquiritigenin on Gemcitabine-induced Capillary Leak Syndrome in Pancreatic Adenocarcinoma via Inhibiting ROS- Mediated Signalling Pathways.

Background: To investigate in-vitro antagonistic effect of low-dose liquiritigenin on gemcitabine-induced capillary leak syndrome (CLS) in pancreatic adenocarcinoma via inhibiting reactive oxygen species (ROS)- mediated signalling pathways.

Materials And Methods: Human pancreatic adenocarcinoma Panc-1 cells and human umbilical vein endothelial cells (HUVECs) were pre-treated using low-dose liquiritigenin for 24 h, then added into gemcitabine and incubated for 48 h. Cell viability, apoptosis rate and ROS levels of Panc-1 cells and HUVECs were respectively detected through methylthiazolyldiphenyl-tetrazoliumbromide (MTT) and flow cytometry.

Traditional Chinese medicine (Shun-Qi-Tong-Xie Granule) for irritable bowel syndrome: study protocol for a randomised controlled trial.

Background: Irritable bowel syndrome (IBS) is a common gastrointestinal functional disorder with no effective therapy. Traditional Chinese medicine (TCM) is one of the most common complementary therapies in China. We designed this study to evaluate the efficacy and safety of Shun-Qi-Tong-Xie Granule (SQTX Granule), a TCM treatment, in patients with IBS with diarrhea (IBS-D).

The efficacy and safety of Jian-Wei-Qu-Tong Pills for the treatment of chronic non-atrophic gastritis (spleen and stomach qi deficiency with damp-heat stasis syndrome): study protocol for a phase II, randomized controlled trial.

Background: Chronic gastritis (CG), a poorly understood entity, is a very common disease of the digestive tract and is difficult to cure. Chronic non-atrophic gastritis (CNG) is the most common type of CG. Even if treated with current standard chemotherapy, some patients will not be freed from this confusing disease.