Publications by authors named "Ruijie Jiao"
Article Synopsis
- Hypopharyngeal squamous cell carcinoma (HSCC) is a dangerous head and neck tumor with a grim outlook, and there’s limited research on its spatial transcriptomics—an advanced technique for analyzing gene expression in tissue samples.
- This study performed spatial transcriptomic analysis on tumor and nearby tissues from four HSCC patients to identify the roles of different cell types, using specific markers for epithelial, fibroblast, and immune cells.
- Results indicated that fibroblasts might play a role in tumor growth, immune infiltration is lower in metastatic lymph nodes compared to primary tumors, and certain favorable prognosis markers were significantly down-regulated in tumor and metastatic tissues.
Objectives: To investigate the characteristics of spatial changes in molars and alveolar bone resorption among patients with loss of mandibular first molars.
Methods: A total of 42 CBCT scans of patients with missing mandibular first molars (3 males, 33 females) and 42 CBCT scans of control subjects without loss of mandibular first molars (9 males, 27 females) were evaluated in this cross-sectional study. All images were standardized using the mandibular posterior tooth plane with Invivo software.