Publications by authors named "Ruijiao Yuan"

Objective: The aim of this study was to identify the active components of Shengxian Decoction (SXT) and to elucidate the multi-component, multi-target, and multi-pathway regulatory mechanisms underlying the efficacy of SXT in treating lung adenocarcinoma (LUAD).

Methods: The effects of SXT extract on proliferation, migration, and invasion capabilities of human LUAD cells were determined through 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), wound healing, and Transwell assays. High-Performance Liquid Chromatography (HPLC) was employed to pinpoint the primary active constituents of SXT.

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Rationale: Pancreatic mixed serous neuroendocrine neoplasm (PMSNN) is an extremely rare disease. Only a few cases on the surgical treatment of PMSNN have been reported in the literature, and it is unclear whether there is invasion of important peripancreatic vessels.

Patient Concerns: We report the case of a 39-year-old female patient with PMSNN accompanied by invasion of important peripancreatic vessels.

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Shengxian Decoction (SXT) is a traditional Chinese medicine prescription comprising several anti-cancer medicinal herbs. However, the anti-cancer effect of SXT has rarely been reported. Herein, we explored the therapeutic potential of SXT for the treatment of lung adenocarcinoma (LUAD).

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Article Synopsis
  • The global pandemic poses challenges for emergency surgeries in elderly patients with high-risk acute abdominal conditions like acute gangrenous cholecystitis.
  • An 89-year-old male with multiple health issues underwent successful emergency laparoscopic cholecystectomy and recovered well despite the risks posed by his age and medical history.
  • Successful emergency surgeries during the pandemic require strict adherence to hospital safety protocols and meticulous preparation and management throughout the process.
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