A bibliometric analysis of research hotspots and trends in transcranial magnetic stimulation and Alzheimer's disease.

Background: Research regarding Transcranial Magnetic Stimulation (TMS) and Alzheimer's disease (AD) has been increasing; however, no bibliometric analysis has yet been conducted in this domain. This study employs bibliometric methods to identify research trends and hotspots concerning AD and TMS.

Methods: We conducted a search in the Web of Science Core Database for articles related to AD and TMS from January 1, 2014, to October 22, 2024.

Efficacy and mechanism of energy metabolism dual-regulated nanoparticles (atovaquone-albendazole nanoparticles) against cystic echinococcosis.

Background: Albendazole (ABZ) and atovaquone (ATO) achieve killing efficacy on Echinococcus granulosus (Egs) by inhibiting energy metabolism, but their utilization rate is low. This study aims to analyze the killing efficacy of ABZ-ATO loading nanoparticles (ABZ-ATO NPs) on Egs.

Methods: Physicochemical properties of NPs were evaluated by ultraviolet spectroscopy and nanoparticle size potentiometer.

Burst firing in Output-Defined Parallel Habenula Circuit Underlies the Antidepressant Effects of Bright Light Treatment.

Research highlights the significance of increased bursting in lateral habenula (LHb) neurons in depression and as a focal point for bright light treatment (BLT). However, the precise spike patterns of LHb neurons projecting to different brain regions during depression, their roles in depression development, and BLT's therapeutic action remain elusive. Here, LHb neurons are found projecting to the dorsal raphe nucleus (DRN), ventral tegmental area (VTA), and median raphe nucleus (MnR) exhibit increased bursting following aversive stimuli exposure, correlating with distinct depressive symptoms.

Prophylactic nicotinamide mononucleotide (NMN) mitigates CSDS-induced depressive-like behaviors in mice via preserving of ATP level in the mPFC.

Depression is a prevalent psychiatric disorder with accumulating evidence implicating dysregulation of extracellular adenosine triphosphate (ATP) levels in the medial prefrontal cortex (mPFC). It remains unclear whether facilitating endogenous ATP production and subsequently increasing extracellular ATP level in the mPFC can exert a prophylactic effect against chronic social defeat stress (CSDS)-induced depressive-like behaviors and enhance stress resilience. Here, we found that nicotinamide mononucleotide (NMN) treatment effectively elevated nicotinamide adenine dinucleotide (NAD) biosynthesis and extracellular ATP levels in the mPFC.

Feruloylated oligosaccharides ameliorate MPTP-induced neurotoxicity in mice by activating ERK/CREB/BDNF/TrkB signalling pathway.

Background: Feruloylated oligosaccharides (FOs) are natural esterification products of ferulic acid and oligosaccharides.

Study Design: In this study, we examined whether FOs contribute to the ensured survival of nigrostriatal dopamine neurons and inhibition of neuroinflammation in Parkinson's disease (PD).

Methods: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP, 30 mg/kg) was injected intraperitoneally into mice to establish a Parkinson's disease (PD) mouse model.

The role of MeCP2 and the BDNF/TrkB signaling pathway in the stress resilience of mice subjected to CSDS.

Rationale: There is accumulating evidence to support the idea that brain-derived neurotrophic factor (BDNF) is involved in stress resilience. However, the precise molecular mechanisms underlying resilience in major depressive disorder (MDD) remain unknown.

Objective: The objective of this study was to explore the role of methyl CpG binding protein 2 (MeCP2) and the BDNF/tropomyosin-receptor-kinase B (TrkB) signaling pathway in the stress resilience to chronic social defeat stress (CSDS) in mice.

The ATP Level in the Medial Prefrontal Cortex Regulates Depressive-like Behavior via the Medial Prefrontal Cortex-Lateral Habenula Pathway.

Background: Depression is the most common mental illness. Mounting evidence suggests that dysregulation of extracellular ATP (adenosine triphosphate) is involved in the pathophysiology of depression. However, the cellular and neural circuit mechanisms through which ATP modulates depressive-like behavior remain elusive.

Super-hydrophobic Cellulose Nanofiber Air Filter with Highly Efficient Filtration and Humidity Resistance.

High-air humidity, especially condensation into droplets under the influence of temperature, can pose a serious threat to air purification filters. This report introduces the use of methyltrimethoxysilane (MTMS) for the silanization hydrophobic modification of cellulose nanofibers (CNFs) and obtains an air filter with super-hydrophobicity (CA = 152.4°) and high-efficiency filtration of particulate matter (PM) through the freeze-drying technology.

Application of diatomite for gallic acid removal from molasses wastewater.

In this study, diatomite was refined by a simple purification method consisting of calcination combined with acid washing. Optimal purification conditions were the focus, including the influence of conditions on diatomite morphology, structure, and specific surface area. The results showed that the optimal conditions were a 550 °C carbonization temperature and 25 wt% HCl.

Effect of Harmine and Its Derivatives Against and Comparison of DNA Damage Targets.

Cystic echinococcosis (CE) is a worldwide zoonotic disease. At present, the treatment options of CE are limited. The main drugs used in clinical chemotherapy of echinococcosis are albendazole and mebendazole, but they mainly exert longterm antiparasitic effects based on high doses.

Preparation and antimicrobial activity of thyme essential oil microcapsules prepared with gum arabic.

Thyme essential oils (TEO) exhibit antimicrobial activities against a wide range of pathogenic microorganisms. Microcapsulation technology can be used to improve the stability, water solubility and antibacterial performance of TEO. In this paper, TEO was selected as the core material, and β-cyclodextrin (β-CD) was the wall material for microcapsulation; gum arabic (GA) was used as an emulsifier to prepare microcapsules by coprecipitation.