Publications by authors named "Ruigeng Wang"
Background: Studies on risk factors of sudden cardiac death (CD) or CD in children with hypertrophic cardiomyopathy (HCM) are lacking.
Objectives: To assess factors associated with the risk of sudden CD or CD in HCM children.
Methods: Pubmed, Embase, Cochrane Library, and Web of Science databases were searched.
[Clinical features of children with severe adenovirus pneumonia and hemophagocytic syndrome: an analysis of 30 cases].
Zhongguo Dang Dai Er Ke Za Zhi
July 2020
Objective: To study the clinical features of children with severe adenovirus pneumonia (SAP) and hemophagocytic syndrome (HPS).
Methods: A retrospective analysis was performed from the chart review data of 30 children with SAP and HPS who were admitted from January 2014 to June 2019. According to the prognosis, the children were divided into a good prognosis group (n=18) and a poor prognosis group (n=12).
Objective: We aimed to assess the prognostic role of liver function alteration with intravenous immunoglobulin (IVIG) resistance in patients with Kawasaki disease (KD) by systematically analyzing and summarizing the results from published studies.
Methods: In this study, we summarized the evidence currently available up to March 31, 2015, and calculated the standard mean difference (SMD) of liver function parameters, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), and total bilirubin between IVIG-responsive and IVIG-resistant patients.
Results: We found that the serum levels of these parameters in IVIG-non-responsive patients were significantly higher than that in IVIG-responsive group (total bilirubin: SMD = 0.
Profiles of responses of immunological factors to different subtypes of Kawasaki disease.
BMC Musculoskelet Disord
October 2015
Background: The responses of immunological factors to different subtypes of Kawasaki disease (KD) remain poorly understood.
Methods: We recruited 388 patients with KD, 160 patients with infectious febrile disease and 85 normal children who served as control subjects. Both the levels and percentages of T lymphocyte subsets, natural killer cells (NK cells) and B cells were analyzed via flow cytometry.
Background: The aim of this study was to investigate the association of congenital heart disease (CHD) with serum ghrelin, tumor necrosis factor-α (TNF-α) and interleukin (IL)-6.
Method: Sixty-three children with CHD, hospitalized between January 2012 and September 2014 at Wuhan Women and Children's Health Care Center, were selected as the study group. Additionally, 28 healthy individuals who had physical examinations at this hospital were selected as the control group.
Objective: To investigate changes in serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) and their significance in children with left-to-right shunt congenital heart disease (CHD) associated with heart failure (HF).
Methods: Twenty healthy children (control group), 20 children with HF, without basic heart disease (HF group), 20 children with left-to-right shunt CHD, without HF (CHD group), and 30 children with left-to-right shunt CHD associated with HF (CHD+HF group) were included in the study. These groups were compared in terms of serum IGF-1 and IGFBP-3 levels.
Objective: To assess the association of nuclear factor-kappa B (NF-κB) and complications of Kawasaki disease (KD) in Chinese children.
Methods: Based on color Doppler examination results, 86 affected children in the KD group were divided into two groups: 39 cases in coronary artery lesion group (CALs subgroup) and 47 cases in non-coronary artery lesion group (Non-CALs subgroup). Infection control group consisted of 65 cases of hospitalized infected children with fever, having same age as the affected children.