Publications by authors named "Ruichao Lu"

Flexible lithium batteries (FLBs) are highly regarded as potential candidates for next-generation batteries due to their versatility in various applications. However, the main focus in the development of FLBs lies in addressing mechanical challenges such as crack propagation under conditions of flexibility and stretchability. Herein, this work presents a novel design of a gel polymer electrolyte (GPE112) film prepared by solution-casting methods.

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Background: Antiretroviral therapy (ART) has transformed HIV management, with various regimens available. Dolutegravir (DTG) plus lamivudine (3TC) dual therapy is now the one of the first line regimens.

Methods: A retrospective, observational study included treatment naïve people living with HIV (PLWH) with baseline HIV RNA viral load (VL) greater than 500,000 copies/mL from March 2020 to June 2022.

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Objectives: Dolutegravir + lamivudine (DTG + 3TC) is a first-line regimen for people with HIV. However, there are still concerns about its efficacy in people with tuberculosis (TB)/HIV due to the lack of available evidence and drug-drug interaction with rifampicin.

Methods: A single-centre retrospective observational case series was conducted in Guangxi Zhuang Autonomous Region, China.

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Background: Existing research has provided evidence of changes in hepatitis delta virus (HDV) prevalence worldwide. This study aimed to investigate the prevalence and molecular characteristics of HDV to elucidate its spread in China.

Methods: A total of 3,000 samples were collected from 2,241 HBV monoinfections and 759 HBV/HIV-1 coinfections across 13 sites in northern, southern, western, and southwestern China.

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Article Synopsis
  • Direct-acting antiviral agents (DAAs) have significantly improved the treatment of Hepatitis C (HCV), but an effective and safe treatment for patients co-infected with HIV remains a challenge, especially in low-resource settings.
  • This study evaluated the safety and efficacy of a 12-week treatment with sofosbuvir and velpatasvir in chronic HCV/HIV-1 co-infected patients who were already on an antiretroviral regimen.
  • Among 243 patients in the study, 97% achieved a sustained virologic response (SVR12) after treatment, demonstrating the high effectiveness of this regimen across different HCV genotypes.
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Drastic capacity decay as a result of active sulfur loss caused by the severe shuttle effect of dissolved polysulfides is the main obstacle in the commercial application of Li-S batteries. Various methods have been developed to suppress the active sulfur loss, but the results are far from ideal. Herein, we propose a facile sulfur compensation strategy to improve the cyclic stability of Li-S batteries.

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Although lithium metal is an ideal anode with high theoretical capacity, Li dendrite formation and volume change have limited its application. We report a vertical polyaniline nanowire-coated carbon nanotube (CNT/PANI) composite flexible electrode on which Li could be homogeneously deposited to obtain a CNT/PANI@Li anode. In the composite, CNT/PANI acted as a host matrix with well-distributed Li ion flux attributed to high electroactive surface area, thereby effectively suppressing the Li dendrite.

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Background: Co-infection with hepatitis C virus (HCV) has become the most common cause of death in human immunodeficiency virus (HIV) infected patients on antiretroviral therapy. The distribution of HCV genotypes varies with geographical regions and time, and limited studies have focused on the HCV genotype in HIV/HCV co-infection.

Methods: The distribution of HCV genotypes was evaluated in 414 patients with HIV/HCV co-infection in three regions (South, Central and Northwest) of China from 2008 to 2010.

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