Sex differences in fetal brain functional network topology.

The fetal period is a critical stage in brain development, and understanding the characteristics of the fetal brain is crucial. Although some studies have explored aspects of fetal brain functional networks, few have specifically focused on sex differences in brain network characteristics. We adopted the graph theory method to calculate brain network functional connectivity and topology properties (including global and nodal properties), and further compared the differences in these parameters between male and female fetuses.

Analysis of surface temperature variation of lakes in China using MODIS land surface temperature data.

China has a great wealth of lake resources over a great spatial extent and these lakes are highly sensitive to climate changes through their heat and water budgets. However, little is known about the changes in lake surface water temperature (LSWT) across China under the climate warming conditions over the past few decades. In this study, MODIS land surface temperature (LST) data were used to examine the spatial and temporal (diurnal, intra-annual, and inter-annual) variations in LSWT of China's lakes during 2001-2016.

Silencing of miR-20b-5p Exerts Inhibitory Effect on Diabetic Retinopathy via Inactivation of Gene Induced VEGF/Akt/PI3K Pathway.

Introduction: Diabetic retinopathy (DR) is a damaging complication of the eye. Studies investigating molecular mechanisms of DR are lacking, leading to poor clinical outcomes. miR-20b-5p is up-regulated in DR.

LncRNA ELFN1-AS1 Promotes Retinoblastoma Growth and Invasion via Regulating miR-4270/SBK1 Axis.

Background: Long noncoding RNA (lncRNA) has been reported to play important roles in tumor initiation. However, how lncRNA ELFN1-AS1 affects retinoblastoma development remains unclear. Thus, we sought to elucidate its functions in retinoblastoma progression.

Identification of driver genes with aberrantly alternative splicing events in pediatric patients with retinoblastoma.

Retinoblastoma (RB) is one of the most common cancer in children. However, the specific mechanism about RB tumorigenesis has not been fully understood. In this study, to comprehensively characterize the splicing alterations in the tumorigenesis of RB, we analyzed the differential alternative splicing events in RB.