Publications by authors named "Rui-Xue Zhai"

This review comprehensively assesses the epidemiology, interaction, and impact on patient outcomes of perioperative sleep disorders (SD) and perioperative neurocognitive disorders (PND) in the elderly. The incidence of SD and PND during the perioperative period in older adults is alarmingly high, with SD significantly contributing to the occurrence of postoperative delirium. However, the clinical evidence linking SD to PND remains insufficient, despite substantial preclinical data.

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Article Synopsis
  • This study examined how the progression of Parkinson's disease (PD) is connected to cognitive impairment and changes in serum levels of uric acid (UA) and homocysteine (Hcy).
  • It involved 74 patients with PD, using the Montreal Cognitive Assessment (MoCA) to categorize their cognitive function, alongside a control group of 60 individuals without PD.
  • Results showed that patients with cognitive impairment had lower UA and higher Hcy levels, with UA being a potential protective factor and Hcy a risk factor for cognitive decline in PD.
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Objective: To investigate the change of lung surfactant protein (SP) A,B,C,D of rats following silica dust exposure in order to provide the evidences for the early diagnosis indices or therapy of silicosis.

Methods: 60 male SD rats were randomly divided into silica group, and corresponding controls group. Rats in silica group were administrated 1 ml silica solution by intratracheal instillation at dose of 50 mg/ml.

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