Publications by authors named "Rui-Ren Zhai"
Article Synopsis
- - The text discusses a case of a 63-year-old male with esophageal cancer who developed hypothyroidism and unusual increases in creatine kinase (CK) and creatinine levels after receiving the PD-1 inhibitor sintilimab.
- - The increase in CK and creatinine matched a decrease in thyroid hormone levels, suggesting that the muscular and renal issues were linked to the hypothyroidism caused by sintilimab.
- - After starting levothyroxine therapy to address the hypothyroidism, the patient's CK and creatinine levels returned to normal, emphasizing the need for awareness of hypothyroidism when evaluating unexplained kidney and muscle issues in patients treated with PD-1 inhibitors.
[Radioprotective effect of rmIL-12 on mice irradiated by γ-ray].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2013
The aim of this study was to investigate the radioprotective effect of recombinant murine interleukin 12 (rmIL-12) on mice irradiated by γ-ray. Fifty- six BALB/c mice were totally irradiated by 6.0 Gy of (60)Co γ-ray and randomly divided into irradiation control group,rmIL-12 treated group and recombinant murine thrombopoietin (rmTPO) treated group.
View Article and Find Full Text PDF[Therapeutic effect of rmIL-12 combined with G-CSF on acute radiation sickness produced by γ-ray irradiation in mice].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2012
The aim of this study is to observe the therapeutic effect of recombinant murine interleukin 12 (rmIL-12) combining with granulocyte colony stimulating factor (G-CSF) on mice irradiated by γ-rays. 56 BALB/c mice were totally irradiated by 6.0 Gy of (60)Co γ-ray and randomly divided into irradiation control group, rmIL-12 treatment group, G-CSF treatment group and combination therapy (rmIL-12 plus G-CSF) group.
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