Publications by authors named "Rui-Qing Zhai"
Constructing a prognostic risk model for Alzheimer's disease based on ferroptosis.
Front Aging Neurosci
April 2023
Article Synopsis
- The study focuses on creating a model to predict how severe Alzheimer's disease might get by looking at changes in certain genes linked to a process called ferroptosis.
- Researchers used data from a database and checked immune cells in samples to analyze differences between two groups.
- They found several important genes that changed with increased levels of a substance called Aβ and believe this model will help doctors treat Alzheimer's disease better.
Family with sequence similarity 72B (FAM72B) has been characterized in the regulation of neuronal development. Nevertheless, the prognostic value of FAM72B expression and its function in the immune microenvironment of lung adenocarcinoma (LUAD) currently remains elusive. In this study, by adopting bioinformatics methodology and experimental verification, we found that FAM72B was upregulated in lung cancer tissues and cell lines, and a higher FAM72B level predicted an unfavorable clinical outcome in LUAD patients.
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