Burden of non-communicable diseases attributable to high temperature in a changing climate from 1990 to 2019: a global analysis.

Background: With global climate change, the health threats of ambient high temperature have received widespread attention. However, latest spatio-temporal patterns of the non-communicable diseases (NCDs) burden attributable to high temperature have not been systematically reported. We aimed to analyze vulnerable areas and populations based on a detailed profile for the NCDs burden attributable to high temperature globally.

Disease burden of COPD attributable to PM in China, Japan and South Korea from 1990 to 2019: a comparative study based on Global Burden of Disease Study 2019.

Objective: We hope to reveal the changing trends of chronic obstructive pulmonary disease (COPD) burden attributable to particulate matter pollution (PM) and its age, period and cohort effects in China, Japan and Korea.

Design: We analysed the trend of COPD disease burden attributable to PM from 1990 to 2019 based on the latest Global Burden of Disease Database (GBD 2019) using JoinPoint model and analysed the effect of age, period and cohort on COPD burden attributable to PM in China, Japan and Korea from 1990 to 2019 using age-period-cohort model (model).

Setting: GBD data from 1990 to 2019.

The Cumulative Effects of the MYH7-V878A and CACNA1C-A1594V Mutations in a Chinese Family with Hypertrophic Cardiomyopathy.

Aims: We investigated the pathogenesis of MYH7-V878A and CACNA1C-A1594V mutations in a Chinese family with hypertrophic cardiomyopathy.

Methods: Clinical, electrocardiographic (ECG), echocardiographic, and cardiac magnetic resonance (CMR) examinations of members of a Chinese family were followed by exon and boarding intron analyses of 96 genes in the proband using second-generation sequencing. We confirmed the mutations by bidirectional Sanger sequencing in the members and in 300 healthy controls.

SbHKT1;4, a member of the high-affinity potassium transporter gene family from Sorghum bicolor, functions to maintain optimal Na⁺ /K⁺ balance under Na⁺ stress.

In halophytic plants, the high-affinity potassium transporter HKT gene family can selectively uptake K⁺ in the presence of toxic concentrations of Na⁺. This has so far not been well examined in glycophytic crops. Here, we report the characterization of SbHKT1;4, a member of the HKT gene family from Sorghum bicolor.

[Analysis on the pharmic chemical component of cerebral cell active factor].

The contents of amino acids, vitamins and chemical elements were determined by LC-60A Shimadzu and P-E3030 made in USA. Results show that drug has 18 kinds of amino acids, 3 kinds of vitamins (not complete) and 20 kinds of chemical elements. The results can provide the referential data for improving the mixture method and clinical administration.