[Immunoregulatory effects of periplocin from Cortex Periplocae in tumor-bearing mice].

Aim: To investigate the immune mechanisms for Periplocin from Cortex Periplocae (CPP) in tumor-bearing mice.

Methods: H(22) tumor-bearing model BALB/c mice were applied to evaluated in vivo immunoregulatory effect of CPP. The influence of different dose CPP (0.

[The effect on the differentiation and maturation of dendritic cells by lupane acetate of cortex periplocae].

Aim: To investigate the effect of lupane acetate of cortex periplocae (CPLA) on the differentiation, maturation and immune activity of human peripheral blood mononuclear cell (PBMC)-derived dendritic cells (DCs) in vitro.

Methods: PBMC isolated from human peripheral blood was cultured with GM-CSF, IL-4 for 5 d and stimulated with TNF-alpha (as positive control) or CPLA to induce DCs. The morphological characteristics of DC were observed under inverted microscope and transmisson electron microscope.