Synopsis of recent research by authors named "Rui-Mo Zhao"
- Rui-Mo Zhao's research focuses on the development of innovative delivery systems, particularly those responsive to reactive oxygen species (ROS), to enhance gene and biomolecule delivery for applications in cancer therapy and immunotherapy.
- His recent work includes the creation of ROS-sensitive lipid nanoparticles and poly(disulfide) vectors that effectively co-deliver therapeutic agents, such as nucleic acids and proteins, to target cells, showing promising results in treating tumors and colitis.
- Zhao's findings emphasize the importance of structural modifications in cationic lipids to improve gene transfection efficiency, revealing how variations in lipid rigidity can influence DNA binding and delivery processes.