Publications by authors named "Rui-Fang Gao"
Article Synopsis
- - The study focused on sequencing a bacteria isolate, Pandoraea sp. 892iso, derived from the plant pathogen Phytophthora rubi and compared its genomic data with 28 other Pandoraea species.
- - A comprehensive genomic analysis was performed, revealing that Pandoraea sp. 892iso is genetically identified as Pandoraea sputorum through multiple phylogenetic and identity assessments.
- - The research suggests that Pandoraea sp. 892iso may act as an endosymbiont for the Phytophthora rubi strain, particularly examining quorum sensing and specific resistance genes.
[Protection effect of baicalin-regulated IKKα on inflammatory reaction of human oral keratinocytes].
Shanghai Kou Qiang Yi Xue
December 2021
Purpose: To observe the regulation of baicalin on IKKα mediated MASPIN in Human oral keratinocytes (HOKs) inflammatory reaction, this study was to explore the molecular regulation mechanism of baicalin on oral mucosal inflammation.
Methods: HOKs were stimulated by lipopolysaccharide (LPS) to mimic the inflammatory response of oral mucosal inflammation in vitro. CCK-8 assay was used to detect the toxicity of baicalin to HOKs; then different concentrations of baicalin were pre-treated to LPS-stimulated HOKs, enzyme-linked immunosorbent assays (ELISA) was used to detect the secretion of IL-6 and TNF-α in LPS-stimulated HOKs; reverse transcription polymerase chain reaction(RT-PCR) and Western blot assay were used to detect the regulatory effects of baicalin on gene and protein expression levels of IKKα mediated MASPIN in LPS-stimulated HOKs.
The data presented here are related to the article entitled "Comparative analysis of genomes reveals oomycete pathogenesis in crops" [1]. These data contain the description of genomic structure of the two plant pathogens, and and characterize several gene families associated with pathogenicity of them: P450, gene families, CAZymes and effector. This data presents the relevant results of two newly sequenced and , so as to provide data for further studies by researchers.
View Article and Find Full Text PDFThe oomycete genus includes devastating plant pathogens that are found in almost all ecosystems. We sequenced the genomes of two quarantined species- and . Comparing these species and related genera allowed reconstruction of the phylogenetic relationships within the genus and revealed genomic features associated with infection and pathogenicity.
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