Publications by authors named "Rui-Bing Niu"
Role of Th2, Th17 and Treg Cells and relevant cytokines in pathogenesis of allergic rhinitis.
Allergy Asthma Clin Immunol
July 2024
Objective: To explore the role of different cells and molecules in the pathogenesis of allergic rhinitis (AR) with positive Artemisia allergen by detecting their expression levels.
Methods: From January 2021 to December 2022,200 AR patients diagnosed in the Otolaryngology Clinic of Ordos Central Hospital were selected as the AR group, and 50 healthy people who underwent physical examination in the hospital during the same period were randomly selected as the healthy control (HC) group. The levels of GATA-3mRNA, RORγtmRNA and FoxP3mRNA in peripheral blood mononuclear cells were detected by real-time fluorescence quantitative PCR (qRT-PCR).
Article Synopsis
- This study investigated how specific gene polymorphisms affect coronary heart disease in Mongolian individuals living in the Ordos area.
- The research involved 200 coronary heart disease patients and 150 healthy controls, analyzing gene variants through real-time polymerase chain reaction.
- Findings indicated that certain genotypes, like SLCO1B *1a/*15, reduced disease risk, while the ε4 allele was linked to a higher risk of coronary heart disease.