Publications by authors named "Rui Sousa Magalhaes"

Article Synopsis
  • - The study developed and validated a new grading score called SB-CLEAR to assess small-bowel cleansing quality for capsule endoscopy (CE), aiming to standardize reporting and improve reliability of findings.
  • - SB-CLEAR scores the small bowel in three sections based on the percentage of visible mucosa, and overall scores classify the quality as excellent, good, or inadequate, with a score of 0-5.
  • - The results showed very strong agreement between observers when using the SB-CLEAR score, confirming its effectiveness as a reliable tool alongside the existing CC-CLEAR for evaluating bowel preparation quality.
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Introduction: In order to optimize the rate of adequate cleansing in colon capsule, it may be important to identify risk factors that can predict a suboptimal colon preparation.

Aim: To define predictive factors for inadequate bowel preparation in colon capsule, according to CC-CLEAR (Colon Capsule CLEansing Assessment and Report).

Methods: Retrospective, single center, cohort study.

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Background/aims: Acute pancreatitis is the most commonly observed adverse event following endoscopic retrograde cholangiopancreatography (ERCP). Early risk stratification is crucial in the management of these patients, to reduce unfavorable outcomes. Multiple prognostic scores are already used in acute pancreatitis, regardless of its etiology.

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Background: Percutaneous endoscopic gastrostomy (PEG) is a useful option for long-term enteral nutrition. Low-profile gastrostomy tubes ("buttons") may afterward be placed in the stomach through the abdominal wall following maturation of the preexisting ostomy. Regular verification is essential since inadequate sizing is associated with accidental exteriorization or food leakage.

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Background: Colon Capsule Cleansing Assessment and Report (CC-CLEAR) is a novel quantitative bowel preparation scale for colon capsule.

Aim: The aim of this study is to validate the association between CC-CLEAR's classification and major CC outcomes: lesion detection rate, surveillance recommendations and post-CC endoscopic treatment.

Methods: Multicentric cohort of consecutive CCs.

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Background And Aim: The RHEMITT score (Renal disease; Heart failure; Endoscopic findings; Major bleeding; Incomplete SBCE; Tobacco; Treatment by enteroscopy) was the first score to accurately predict the individual risk of small bowel rebleeding after capsule endoscopy (SBCE). The aim of the study is on the prospective validation of the RHEMITT score.

Methods: Cohort of consecutive patients with mid-gastrointestinal bleeding (MGIB) submitted to SBCE and followed prospectively, during at least 12 months, since 2017 until 2020.

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Article Synopsis
  • A 42-year-old woman with ulcerative colitis developed pyoderma gangrenosum (PG) on her left leg, which was painful and ulcerated.
  • Initial treatments, including oral prednisolone, were ineffective, so she was switched to adalimumab; however, PG worsened and became superinfected.
  • After combining adalimumab with antibiotics, daily wound care, and hyperbaric oxygen therapy, the PG significantly improved, leading to full remission and recovery of her left foot's function.
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Article Synopsis
  • Non-alcoholic fatty liver disease (NAFLD) is a widespread chronic liver condition, and transient elastography (Fibroscan) measures liver fat content to evaluate its severity and potential cardiovascular (CV) risk.* -
  • In a study of 96 NAFLD patients, it was found that a higher controlled attenuation parameter (CAP) value, along with factors like type 2 diabetes, dyslipidaemia, and smoking, significantly increased the risk of cardiovascular events.* -
  • The findings suggest that a CAP value above 295 dB/m is linked to an eight-fold increase in cardiovascular event risk, highlighting the importance of using transient elastography in assessing CV risk in NAFLD patients.*
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Background: Perianal disease is associated with a disabling course of Crohn's disease (CD). We aim to study the impact of perianal disease on CD remission rates, after a 1-year course of infliximab in combination therapy with azathioprine.

Methods: This was a retrospective, single-center cohort study, including consecutive CD patients on combination therapy, followed for 1 year since induction.

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Background And Aims: Current colon capsule (CC) cleansing grading scales rely on subjective parameters and lack proper interobserver agreement. We should strive for higher intra- and interobserver agreement for the evaluation of the cleansing quality of CCs. Here we sought to validate a new grading scale for the evaluation of CC cleansing.

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Percutaneous Endoscopic Gastrostomy (PEG) is accepted as an efficient method to provide long-term enteral nutrition. PEG accidental dislodgement (device exteriorization confirmed by expert evaluation) rate is high and can lead to major morbidity. To identify independent risk factors for PEG accidental dislodgement.

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Introduction: Small bowel capsule endoscopy (SBCE) is the gold standard for mid-gastrointestinal bleeding (MGIB). No score has been developed to predict the risk of small bowel rebleeding after SBCE.

Objective: Creating a predictive small bowel rebleeding risk score for MGIB, after initial SBCE.

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In suspected Crohn's disease (CD), non-diagnostic ileocolonoscopies are often followed by small bowel capsule endoscopy (SBCE). Adequate pre-selection of patients for SBCE is a key to optimize allocation of resources. We aimed to establish a rational approach for the CD diagnostic workflow, based on biochemical profile of patients with suspected CD, targeting an optimization of patients' selection for SBCE.

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