The microstrip patch antenna exhibits frequency stability under temperature variations, making it suitable for applications in the Industrial Internet, resource extraction, structural health monitoring, and other fields. A low-profile complementary split ring resonator (CSRR) structure is introduced into the radiating patch of the antenna, confining the electric field energy within a small region inside the ring. This design significantly enhances the antenna's sensitivity to changes in the dielectric constant.
View Article and Find Full Text PDFWild rice, as the ancestor of cultivated rice, has accumulated a wide range of beneficial traits through prolonged natural selection and evolution. Oryza officinalis, belonging to the CC genome, differs significantly from the AA genome. In this study, we utilized second- and third-generation sequencing, along with Hi-C technology, to assemble the genome of MT10 (O.
View Article and Find Full Text PDFCadmium (Cd) is a non-essential heavy metal that is highly toxic to testicle. Selenium (Se) is known to possess antagonistic effects against Cd toxicity, yet the precise mechanisms through which Se counteracts Cd-induced testicular damage in chickens through Nuclear factor erythroid 2-related factor 2/Heme oxygenase-1 (Nrf2/HO-1) signaling pathway, oxidative stress (OS), apoptosis, and inflammation remained unclear. In the present study, the experimental model of chicken testis was established by incorporating CdCl and NaSeO into the dietary intake.
View Article and Find Full Text PDFFerroelectric polymers for energy storage and conversions suffer from high energy losses. Despite great efforts in polymer composites with organic or inorganic fillers, limited successes are achieved with an often compromised dielectric constant (K). Here, a synthesized organic-inorganic hybrid-perfluorinated polyhedral oligomeric silsesquioxane (F-POSS) is presented for creating an ultralow-loss ferroelectric polymer composite.
View Article and Find Full Text PDFMicromachines (Basel)
February 2025
This paper presents a silicon-based wafer-level vacuum packaging platform with a monolithically integrated micro-oven. This system provides vacuum and constant temperature operating conditions to improve the performance of resonant micro-electro-mechanical systems (MEMS) devices. Based on a three-layer wafer-level vacuum packaging process, the platform integrates a silicon thermistor, a thermal isolation structure, and a heater with the addition of a mask and an additional silicon wafer.
View Article and Find Full Text PDFBrain tumors provide unique insights into brain plasticity due to their slow growth compared to acute cerebrovascular diseases. Despite relying on sophisticated functional networks, patients with brain tumors exhibit minimal deficits in higher language functions and demonstrate positive post-injury plasticity; however, the underlying neural mechanisms remain unclear. We utilized high-density electroencephalography to investigate language network plasticity in brain tumor patients without evident language deficits.
View Article and Find Full Text PDFBackground: Microcystin-LR (MC-LR) is a hepatotoxin produced by cyanobacteria, which is biologically toxic, prevalent, and has serious effects on human health. Therefore, it is urgent to develop miniaturized and cost-efficient methods for MC-LR monitoring. Photocatalytic fuel cell (PFC) sensing has already been tipped as a promising approach for facile, on-site detection in environmental mediators.
View Article and Find Full Text PDFInt Immunopharmacol
April 2025
Myocardial infarction and heart failure represent major global health challenges, leading causes of hospitalization and mortality worldwide, especially among the elderly. Despite considerable advancements in treatment, there remains a substantial need to improve prognostic outcomes through further research into pathogenesis and therapeutic optimization. S100 proteins, as inflammatory factors within the heart, demonstrate binding capabilities to various target proteins.
View Article and Find Full Text PDFAlzheimer's disease (AD) is the most prevalent neurodegenerative disease, characterized by memory decline and behavioral changes. Its pathological features include senile plaques, neurofibrillary tangles, and reactive gliosis, comprising abnormal accumulations of β-amyloid peptide (Aβ) and hyperphosphorylated tau protein surrounded by reactive astrocytes and microglia. Recently, it has emerged that severe reactive astrocytes and MAOB-dependent production of GABA and HO are the real causes of learning and memory impairment and neurodegeneration.
View Article and Find Full Text PDFIn this study, we predicted the global climatic suitability of , using maximum entropy (MaxEnt) modeling. We used species' natural occurrence records in 1981-2024 and environmental variables in 1981-2010, reflecting near-current climate conditions, for modeling. The occurrence records used for modeling excluded the data from greenhouses and summer-only presence.
View Article and Find Full Text PDFIt has become increasingly recognised that MATN1-AS1 is involved in multiple tumour development. The role of MATN1-AS1 in clear cell renal cell carcinoma (ccRCC), however, is still largely unrecognised. This study investigated the molecular functions of MATN1-AS1 in promoting ccRCC metastasis and sunitinib resistance.
View Article and Find Full Text PDFThe current status of multi-mycotoxin contamination in edible and medicinal plants demands urgent development of high-throughput analytical methods for mycotoxin detection. In this study, a reliable and sensitive method for the simultaneous analysis of 73 mycotoxins was established and successfully applied to detect mycotoxins in 260 samples of four dual-purpose plants (lotus seed, coix seed, licorice root, and dried tangerine peel). Sample preparation involved optimized QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) extraction combined with liquid-liquid extraction purification, and an enhanced ion pair library was established to reduce matrix interference and improve the method's universality.
View Article and Find Full Text PDFObjective: The interaction between T cells, particularly naïve CD4 T cells (CD4Tn), and colorectal cancer (CRC) is highly complex. CD4Tn play a crucial role in modulating immune responses within the tumor microenvironment, yet the precise mechanisms by which they influence tumor progression remain elusive. This study aims to explore the relationship between CRC and CD4Tn, identify biomarkers and therapeutic targets, and focus on the role of CD4Tn in shaping the immune environment of CRC.
View Article and Find Full Text PDFGreen algal blooms (GABs) have become a global concern and are particularly serious in the southern Yellow Sea (SYS). Remote sensing (RS) images are the most popular and effective data source for detecting GABs; however, in case of unfavorable weather conditions (e.g.
View Article and Find Full Text PDFExcessive histamine in spoiled seafood poses considerable health hazards to consumers, yet its detection is challenging due to complicated sample preparation and detection methodologies. Herein, an integrated colorimetric platform containing Poly (vinyl alcohol) (PVA)/hyaluronic acid (HA) microneedle patches-assisted extraction and aptasensor-based detection was reported. The developed PVA/HA microneedle patches facilitated on-site histamine extraction from seafood through a two-minute press-and-peel procedure.
View Article and Find Full Text PDFLinezolid is an oxazolidinone antibiotic that is mainly permitted to treat Gram-positive bacterial infections. Recent studies have shown that linezolid also has antibacterial effects on several other bacteria outside the package insert, including , non-tuberculous mycobacteria (NTM), , , and anaerobes, . Interestingly, linezolid also has an inhibitory effect on fungi.
View Article and Find Full Text PDFTriplet excitons, driven by spin-flip processes, play a crucial role in enabling efficient room-temperature phosphorescence across various applications. However, attaining a significant accumulation of long-lived excitons is impeded by the simultaneous influence of nonradiative and radiative decay pathways alongside intersystem crossing efficiencies. Here, we introduce a solvent intercalation approach that leverages the triplet exciton processes in a family of zero-dimensional organic-inorganic halides, AZnBr (A = organic phosphonium cations).
View Article and Find Full Text PDFRed yeast rice is a nutraceutical fermented product used worldwide for the symptomatic relief of dyslipidemia and cardiovascular disease. However, the fermentation-induced lipid transformation from rice to red yeast rice remains unclear. Herein, an ultra-high performance liquid chromatography coupled with hybrid quadrupole-orbitrap mass spectrometry method was developed for the comprehensive lipid analysis during fermentation.
View Article and Find Full Text PDFBaicalin is a natural flavonoid compound with a wide range of biological activities, including anti-oxidant and anti-inflammatory properties. Previous we found that the abundance of baicalin in bovine serum is significantly higher than in ovine serum at mid-lactation. It suggests that baicalin may play a role in the regulation of lactation performance.
View Article and Find Full Text PDFObjective: In China, motor vehicles and non-motorized vehicles (bicycles or e-bikes) are the most common modes of transportation. However, individuals with epilepsy may face significant challenges and barriers when using these modes of transportation. This study aims to assess the current status and challenges faced by people with epilepsy in terms of transportation.
View Article and Find Full Text PDFObjective: The unsafe behaviors and great stress during the critical takeover process cause safety issues in conditionally automated driving. To compensate for the limitations of existing performance improvement methods, the current study aims to reduce unsafe behaviors during the critical takeover process by correcting driver cognitions.
Methods: This study proposed a behavioral inoculation approach against unsafe takeover behaviors.
Due to the difference of estrogen levels in different phases of estrous cycle, it is necessary to exclude the influence of endogenous estrogen when studying the cardiovascular effects of estrogen and its analogues. In this study, the ischemia/reperfusion (I/R) injury of isolated heart were investigated in female rats during different phases of estrous cycle with male rats as comparison. The results indicated that the estrogen content in blood of rats during metestrus and diestrus (MD) was lower than those during proestrus and estrous (PE).
View Article and Find Full Text PDFObjective: Nonmelanoma skin cancer (NMSC) is a common malignancy that starts in the top layer of the skin. Exposure to heavy metals has been suggested to increase the risk of skin cancer. Cadmium, prevalent in various industries and present in cigarette smoke, has been implicated in potential skin effects in animal studies.
View Article and Find Full Text PDFExpert Opin Biol Ther
March 2025
Introduction: Clinical experience with anti-interleukin (IL)-5 biologic therapies for severe asthma has been increasing, alongside deeper and broader research focusing on the role of IL-5 and the IL-5 targeted mepolizumab. This review aims to provide an update of the evidence on the role of IL-5 and mepolizumab, with discussions of the benefits of mepolizumab and its future potential, to promote the comprehension of the pathophysiology and therapeutic approaches to asthma.
Areas Covered: For this narrative review, we conducted a database search in PubMed and Embase using the keywords 'IL-5' and 'mepolizumab,' focusing on randomized controlled trials and real-world studies up to September 2024.