Publications by authors named "Ruhua Guan"

Article Synopsis
  • * Results showed that Beclin-1 and LC3-II levels were significantly lower in PTC tissues compared to normal tissues, and this decreased expression was linked to lymph node metastasis.
  • * The findings suggest a decline in autophagic activity in PTC, which may play a role in the cancer's development.
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Article Synopsis
  • Long noncoding RNAs (lncRNAs) play a crucial role in regulating gene expression and are linked to various cancers, but their specific role in papillary thyroid carcinoma (PTC) is not well understood.
  • In this study, researchers used lncRNA microarrays to analyze differences in lncRNA and mRNA expression between PTC samples and adjacent normal tissue, finding 675 lncRNAs and 751 mRNAs with abnormal expression levels.
  • The findings suggest new lncRNAs associated with PTC that could be potential targets for improving diagnosis and treatment, as well as insights into various cellular pathways affected in the disease.
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This systematic review assessed the safety and efficacy of the disposable circumcision suture device (DCSD) and conventional circumcision (CC) in the treatment of redundant prepuce and phimosis. Two independent reviewers conducted a literature search for randomized controlled trials (RCTs) using the DCSD and CC for the treatment of redundant prepuce or phimosis in China and abroad. Nine RCTs (1898 cases) were included.

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