Publications by authors named "Ruhi Thakur"

Article Synopsis
  • - Fluoride toxicity is a growing global concern, particularly affecting male reproductive health, as it can lead to fertility issues and various biochemical changes in the reproductive system.
  • - Research from multiple sources reveals that fluoride exposure can damage sperm quality and production, leading to structural defects in sperm and decreased testosterone levels, which ultimately contribute to infertility.
  • - Understanding the impacts of fluoride is crucial for public health, as this can inform safe exposure guidelines and develop treatments to counteract fluoride-induced reproductive damage.
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This review explores the diverse effects of fluoride on pancreatic function, encompassing both in vitro and in vivo studies. Fluoride exposure induces notable alterations at the cellular and molecular levels, affecting pancreatic morphology, histology, and enzymatic activity. In vitro studies demonstrate significant inhibition of pancreatic α-amylase activity and apoptosis in pancreatic beta cells.

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Considerable integrative efforts have been made to investigate the effects of fluoride on female reproductive organs since the last years. The ingestion of fluoride causes adverse effects on human health like causing skeletal fluorosis, dental fluorosis, bone fractures, kidney problems, decrease birth rates, weakening of thyroid functionality, and impair intelligence, particularly in children. In this review, we discuss the adverse effects of fluoride on female reproductive organs and presented certain remedies.

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