Publications by authors named "Ruggiero H"
Heparin has been used intensively in the treatment of acute myocardial infarction and preinfarction angina (PA) at full doses as a single drug by us. However, heparin may be used at smaller doses for similar purposes. These doses are not exactly anticoagulant, even though they reduce blood hypercoagulability, and act mainly in an antithrombotic capacity.
View Article and Find Full Text PDF[Treatment of neurological forms of Argentinian hemorrhagic fever with cytarabine].
Pathol Biol (Paris)
September 1987
Article Synopsis
- Cytarabine was tested on 125 patients with neurological forms of Argentina Hemorrhagic Fever, resulting in a mortality rate of 12.88%.
- In contrast, untreated patients had a much higher mortality rate of 61.40%.
- The treatment is most effective when administered early, and no side effects were reported.
During the 23 consecutive annual epidemics of Argentine haemorrhagic fever observed from 1959 to 1983, a group of 4,433 patients were treated at Junin (Argentina) with convalescent's plasma; the overall mortality rate was 3.29%. In 1958, before convalescent's plasma was used, the mortality rate in 448 patients who received the conventional treatment was 42.
View Article and Find Full Text PDFThe effects of heparin were studied in a group of 42 patients with preinfarction angina (PA) and acute myocardial infarction (AMI) whose plasma fibrinogen was increased. Plasma fibrinogen was measured by the turbidimetric method in timol turbidimetric units. Statistically significant results proved that heparin reduces the plasma fibrinogen progressively over a treatment period of 6 weeks.
View Article and Find Full Text PDF[Medical treatment of the threat syndrome with heparin. Long-term prospective study].
Ann Cardiol Angeiol (Paris)
May 1983
A 19-year study of 119 patients stricken with a threat syndrome and treated with heparin is presented. The average observation period is 10.15 years.
View Article and Find Full Text PDFArticle Synopsis
- The study examined how heparin impacts blood viscosity in patients with acute myocardial infarction and preinfarction angina, noting that their blood viscosity levels were elevated.
- Heparin was found to significantly reduce plasma viscosity right after administration, while having a lesser effect on serum and whole blood viscosity.
- The research concluded that heparin's ability to lower blood viscosity and related factors like fibrinogen and hematocrit is crucial in managing conditions like AMI and PA, which are characterized by hyperviscosity and hypercoagulability.
A procedure that allows to ascertain a diagnosis of Argentine Hemorrhagic Fever (AHF) as early as 24-48 hours after onset of symptoms is described. An immunofluorescent (IF) test on round cells of urinary sediment was employed. The procedure was assayed on 31 patients with febrile syndrome during epidemic peaks of 1975-1976.
View Article and Find Full Text PDFArticle Synopsis
- A study examined 267 volunteers vaccinated against Argentine hemorrhagic fever with the XJCl3 strain of Junin virus, focusing on their health status seven to nine years post-vaccination.
- Clinical and laboratory tests showed normal results, indicating no long-term health issues linked to the virus among participants.
- Of the 165 sera tested, 90.3% had detectable neutralizing antibodies, suggesting that most maintained immunity from the vaccine, while only 9% likely experienced reinfection, similar to the expected rate of subclinical infections in the area.
[Biphasic course in Argentine hemorrhagic fever. Report of a case].
Medicina (B Aires)
September 1970