Hemivertebra resection by a posterior approach: innovative operative technique and first results.

Study Design: A retrospective study was conducted, with clinical evaluation of hemivertebra resection using transpedicular instrumentation by a posterior approach in young children.

Objective: To assess a new method of early intervention in congenital scoliosis by a posterior approach.

Summary Of Background Data: Previously described surgical procedures are fusion in situ, hemiepiphyseodesis and arthrodesis, "growing" instrumentations, and hemivertebra resections performed by a combined anterior and posterior approach.

[Homosexual pedophilia and functional networks - An fMRI case report and literature review].

Pedophilia is a complex bio-psycho-social disorder often associated with serious offending. Knowledge about neurobiological correlates that could serve as diagnostic and maybe even as prognostic markers is limited. FMRI examination, which shows neuronal activation in vivo and therefore represents a neurobiological correlate, was not done in pedophilia so far.

Pocket Semiquinonate Complexes of Cobalt(II), Copper(II), and Zinc(II) Prepared with the Hydrotris(cumenylmethylpyrazolyl)borate Ligand.

3,5-Di-tert-butyl-1,2-semiquinonate (3,5-DBSQ) complexes of Co(II), Cu(II), and Zn(II) have been prepared that contain the hydrotris(cumenylmethyl-pyrazolyl)borate (Tp(Cum,Me)) coligand. Tp(Cum,Me)Zn(3,5-DBSQ) and Tp(Cum,Me)Cu(3,5-DBSQ) were prepared by treating the parent hydroxide, Tp(Cum,Me)M(OH), M = Cu and Zn, with 3,5-di-tert-butylcatechol. Tp(Cum,Me)Co(3,5-DBSQ) was prepared by a reaction between (Tp(Cum,Me))(2)Co and 3,5-DBCat.

Alcohol-associated stimuli activate the ventral striatum in abstinent alcoholics.

Alcohol-associated cues may act as conditioned stimuli that activate the brain reward system and motivate alcohol intake in alcoholics. Alcohol-associated visual stimuli were presented during functional magnetic resonance imaging. An activation of the ventral putamen was observed in alcoholics but not in control subjects.

Excision of uranium oxide chains and ribbons in the novel one-dimensional uranyl iodates K(2)[(UO(2))3(IO(3))(4)O(2)] and Ba[(UO(2)2(IO(3))(2)O(2)](H(2)O).

The alkali metal and alkaline-earth metal uranyl iodates K(2)[(UO(2))(3)(IO(3))(4)O(2)] and Ba[(UO(2))(2)(IO(3))(2)O(2)](H(2)O) have been prepared from the hydrothermal reactions of KCl or BaCl(2) with UO(3) and I(2)O(5) at 425 and 180 degrees C, respectively. While K(2)[(UO(2))(3)(IO(3))(4)O(2)] can be synthesized under both mild and supercritical conditions, the yield increases from <5% to 73% as the temperature is raised from 180 to 425 degrees C. Ba[(UO(2))(2)(IO(3))(2)O(2)](H(2)O), however, has only been isolated from reactions performed in the mild temperature regime.

Antipsychotic drug effects on motor activation measured by functional magnetic resonance imaging in schizophrenic patients.

Brain function and laterality in schizophrenia were investigated by means of a simple motor task with a self-generated left-hand sequential finger opposition (SFO) using a whole-brain high-speed (100 ms per slice) functional imaging technique. Neuroleptic-naïve, acutely ill schizophrenic patients were compared to schizophrenic patients under stable neuroleptic medication and matched controls. The goal was to evaluate both the motor function in first-episode patients and possible effects of different neuroleptic treatments on functional MRI results.

[Medial medullary infarct].

Medial medullary infarct is a rare type of brain stem infarction first described in 1908. It was only since the broad use of MRI that an accurate clinical topographical correlation could be documented in survivors. We observed two patients; one of them had an anteromedial unilateral infarction in the upper medulla, and the clinical picture was characterized by contralateral hemiparesis, facial weakness, dysarthria and palatal weakness.

Methoxide Coordination at the Pocket of [Cu Tp Me] and a Simple Model for the Cu Center of Galactose Oxidase.

An unusually negative oxidation potential is found for the tyrosine residue in the center of fungal galactose oxidase. The complex [Cu(Tp ){O(MeS)C H }] (see picture on the right; Tp =hydrotris(pyrazolyl)borate) offers insight into the mode of (cysteinyl-tyrosine) coordination to the copper center, and the reason for the low oxidation potential.

Streptokinase-induced activation of the kallikrein-kinin system and of the contact phase in patients with acute myocardial infarction.

Thrombolytic therapy in acute myocardial infarction (AMI) is hampered by a considerable reocclusion rate. Thrombin activity is enhanced, and contact-system activation via plasminemia might be possible. Prospectively we examined the contact phase and the kallikrein-kinin system and additional molecular markers of hemostasis and fibrinolysis in AMI.

Pyrazolylborate-Zinc Complexes of RNA Precursors and Analogues Thereof.

The Tp ligand tris(3-cumenyl-5-methylpyrazolyl)borate was found to stabilize zinc complexes of nucleobases, of their natural precursors, and of nucleoside and nucleotide derivatives. Dihydroorotic acid and orotic acid are bound as monodentate carboxylate ligands. Uracil is coordinated via its deprotonated N1; 6-methylthiouracil acts as a bidentate ligand via N1 and S.

Small Molecule Chemistry of the Pyrazolylborate-Zinc Unit Tp(Cum,Me)Zn.

The synthesis of the highly encapsulating pyrazolylborate ligand hydrotris(3-p-cumenyl-5-methylpyrazolyl)borate (L = Tp(Cum,Me)) and of its zinc hydroxide complex L.Zn-OH (1) are described. 1 is converted by H(2)S into the hydrosulfide complex L.

Contrast sensitivity with monofocal and bifocal intraocular lenses.

Bifocal intraocular lenses (BIOLs) reduce image contrast. We measured contrast sensitivity (CS) to evaluate the clinical significance of the loss in image contrast. Four groups were compared: 15 patients with a monofocal IOL, 13 with the True Vista BIOL, 13 with the AcuraSee BIOL, 11 with the diffractive BIOL.

Structure and expression of the gene coding for the alpha-subunit of DNA-dependent RNA polymerase from the chloroplast genome of Zea mays.

The rpoA gene coding for the alpha-subunit of DNA-dependent RNA polymerase located on the DNA of Zea mays chloroplasts has been characterized with respect to its position on the chloroplast genome and its nucleotide sequence. The amino acid sequence derived for a 39 Kd polypeptide shows strong homology with sequences derived from the rpoA genes of other chloroplast species and with the amino acid sequence of the alpha-subunit from E. coli RNA polymerase.