Publications by authors named "Rudy E Cozett"
Org Biomol Chem
November 2016
Article Synopsis
- A series of 4-PPY C-3 carboxamides with peptide side chains were created and tested for their ability to resolve chiral benzylic secondary alcohols.
- The design emphasized using a tryptophan residue to enhance π-stacking interactions, supported by structure-based modeling techniques.
- A specific catalyst with a LeuTrp-N-Boc side chain showed promising results, providing enantioselectivity values slightly over 10, highlighting the role of modeling in improving catalyst performance for potential large-scale applications.
