Molecular alteration in the Gap Junction Beta 2 () gene associated with non-syndromic sensorineural hearing impairment.

Non-syndromic sensory neural hearing defect is one of the genetic diseases inherited from parents to offerings. The autosomal recessive form affects a large population worldwide and has become a major concern in the social and professional lives of many people. There are many factors and genes which are involved in hearing loss but the Gap Junction Beta 2 () gene which encodes the connexin 26 protein, is a major cause of non-syndromic recessive deafness (NSRD).