Characterization of Orthophosphate and Orthovanadate in Aqueous Solution Using Polarized Raman Spectroscopy.

Polarized Raman spectroscopy was used to analyze aqueous solutions of sodium orthophosphate and orthovanadate over a wide concentration range (0.00891-0.702 mol/L) at 23 °C.

Indigofera cryptantha-induced pigmenturia in cattle in South Africa.

Two field cases of reddish-black pigmenturia occurred where cattle grazed on an established Cenchrus ciliaris (blue buffalo grass) pasture in South Africa. The pasture was noticeably invaded by Indigofera cryptantha, which was heavily grazed. Apart from the discolored urine, no other clinical abnormalities were detected.

Prioritised identification of structural classes of natural products from higher plants in the expedition of antimalarial drug discovery.

The emergence and spread of drug-recalcitrant Plasmodium falciparum parasites threaten to reverse the gains made in the fight against malaria. Urgent measures need to be taken to curb this impending challenge. The higher plant-derived sesquiterpene, quinoline alkaloids, and naphthoquinone natural product classes of compounds have previously served as phenomenal chemical scaffolds from which integral antimalarial drugs were developed.

Leveraging off higher plant phylogenetic insights for antiplasmodial drug discovery.

The antimalarial drug-resistance conundrum which threatens to reverse the great strides taken to curb the malaria scourge warrants an urgent need to find novel chemical scaffolds to serve as templates for the development of new antimalarial drugs. Plants represent a viable alternative source for the discovery of unique potential antiplasmodial chemical scaffolds. To expedite the discovery of new antiplasmodial compounds from plants, the aim of this study was to use phylogenetic analysis to identify higher plant orders and families that can be rationally prioritised for antimalarial drug discovery.

Evaluation of Lower Leg Arteries and Fibular Perforators before Microsurgical Fibular Transfer Using Noncontrast-Enhanced Quiescent-Interval Slice-Selective (QISS) Magnetic Resonance Angiography.

(1) Background: Preoperative imaging of the lower leg arteries is essential for planning fibular grafting. The aim of this study was to evaluate the feasibility and clinical value of non-contrast-enhanced (CE) Quiescent-Interval Slice-Selective (QISS)-magnetic resonance angiography (MRA) for reliably visualizing the anatomy and patency of the lower leg arteries and for preoperatively determining the presence, number, and location of fibular perforators. (2) Methods: The anatomy and stenoses of the lower leg arteries and the presence, number, and location of fibular perforators were determined in fifty patients with oral and maxillofacial tumors.

Correction: Zinc(II) hydration in aqueous solution. A Raman spectroscopic investigation and an molecular orbital study.

Correction for 'Zinc(II) hydration in aqueous solution. A Raman spectroscopic investigation and an molecular orbital study' by Wolfram W. Rudolph , , 1999, , 4583-4593, https://doi.

Comparative Study of Different Diagnostic Routine Methods for the Identification of .

Recent publications indicate that can cause infections in humans, even though it is rarely reported in routine diagnostics. However, the fact that it is infrequently detected may be explained by the misidentification of the species by conventional methods. It is also likely that is not considered clinically relevant and therefore not consistently included in diagnostic results.

Population pharmacokinetics and probability of target attainment in patients with sepsis under renal replacement therapy receiving continuous infusion of meropenem: Sustained low-efficiency dialysis and continuous veno-venous haemodialysis.

Aims: To describe the population pharmacokinetics (PK) and probability of target attainment (PTA) of continuous infusion (CI) of meropenem in septic patients receiving renal replacement therapy (RRT).

Methods: Fifteen patients without RRT, 13 patients receiving sustained low-efficiency dialysis and 12 patients receiving continuous veno-venous haemodialysis were included. Population PK analysis with Monte Carlo simulations for different dosing regimens was performed.

Hydration and Ion-Pair Formation of NaNO(aq): A Vibrational Spectroscopic and Density Functional Theory Study.

Qualitative and quantitative Raman and infrared measurements on sodium nitrate (NaNO) solutions have been carried out over a wide concentration range (5.56 × 10-7.946 mol/L) in water and heavy water.

Picowatt calorimeter for optical absorption spectroscopy.

An optical picowatt calorimeter at 4 K is demonstrated to measure absorption spectra from 330 nm to 1700 nm of optical samples. The minimum detectable absorbed power is 10 pW, resulting in absorption sensitivities of 0.3 ppm for 30 µW of incident power from a tunable source and 0.

Nanolaminate-based design for UV laser mirror coatings.

With ever-increasing laser power, the requirements for ultraviolet (UV) coatings increase continuously. The fundamental challenge for UV laser-resistant mirror coatings is to simultaneously exhibit a high reflectivity with a large bandwidth and high laser resistance. These characteristics are traditionally achieved by the deposition of laser-resistant layers on highly reflective layers.

Comparison of VITEK 2, MALDI-TOF MS, 16S rRNA gene sequencing, and whole-genome sequencing for identification of Roseomonas mucosa.

The bacterial species Roseomonas mucosa is pathogenic in humans, and although it is rarely detected during routine diagnostics, it is becoming increasingly important clinically. For a long time, R. mucosa was regarded as a classic environmental bacterium.

On the Hydration of Heavy Rare Earth Ions: Ho, Er, Tm, Yb and Lu-A Raman Study.

Raman spectra of aqueous Ho, Er, Tm, Yb, and Lu-perchlorate solutions were measured over a large wavenumber range from 50-4180 cm. In the low wavenumber range (terahertz region), strongly polarized Raman bands were detected at 387 cm, 389 cm, 391 cm, 394 cm, and 396 cm, respectively, which are fairly broad (full widths at half height at ~52 cm). These isotropic Raman bands were assigned to the breathing modes, ν Ln-O of the heavy rare earth (HRE) octaaqua ions, [Ln(HO)].

Detection of Robinsoniella peoriensis in multiple bone samples of a trauma patient.

We report a case of a 58-year-old male patient who underwent several surgeries following an accident. The bacterium Robinsoniella peoriensis was detected independently in multiple samples from both the right talus and tibia. The bacterium could only be identified using 16S rRNA gene sequencing.

Liquid chromatography-mass spectrometry-based determination of ergocristine, ergocryptine, ergotamine, ergovaline, hypoglycin A, lolitrem B, methylene cyclopropyl acetic acid carnitine, N-acetylloline, N-formylloline, paxilline, and peramine in equine hair.

Ingestion of hypoglycin A (HGA) in maple seeds or alkaloids produced by symbiotic fungi in pasture grasses is thought to be associated with various syndromes in grazing animals. This article describes analytical methods for monitoring long-term exposure to HGA, its metabolite MCPA-carnitine, as well as ergocristine, ergocryptine, ergotamine, ergovaline, lolitrem B, N-acetylloline, N-formylloline, peramine, and paxilline in equine hair. After extraction of hair samples separation was achieved using two ultra high performance liquid chromatographic systems (HILIC or RP-C18, ammonium formate:acetonitrile).

Mid IR hollow core fiber gas laser emitting at 4.6 μm.

Emission at 4.6 μm was observed from an NO filled hollow core fiber laser. 8-ns pump pulses at 1.

Comparative study on the metabolism of the ergot alkaloids ergocristine, ergocryptine, ergotamine, and ergovaline in equine and human S9 fractions and equine liver preparations.

1. Ergopeptine alkaloids like ergovaline and ergotamine are suspected to be associated with fescue toxicosis and ergotism in horses. Information on the metabolism of ergot alkaloids is scarce, especially in horses, but needed for toxicological analysis of these drugs in urine/feces of affected horses.

Hydration and Ion Pair Formation in Aqueous Lu- Solution.

Aqueous solutions of Lu- perchlorate, triflate and chloride were measured by Raman spectroscopy. A weak, isotropic mode at 396 cm (full width at half height (fwhh) at 50 cm) was observed in perchlorate and triflate solutions. This mode was assigned to the totally symmetric stretching mode of [Lu(OH₂)₈], ν₁LuO₈.

Laser resistance dependence of interface for high-reflective coatings studied by capacitance-voltage and absorption measurement.

HfO/SiO bilayer coatings and multilayer high-reflection coatings without and with a modified co-evaporated interface (MCEI) have been prepared. An MCEI is designed to be evaporated at an oxygen-deficient environment to achieve higher absorption than the conventional discrete interface. Capacitance-voltage measurements and absorption measurements demonstrate that an MCEI increases the trap density and leads to higher absorption.

Optical properties of oxygen vacancies in HfO thin films studied by absorption and luminescence spectroscopy.

Hafnium oxide thin films with varying oxygen content were investigated with the goal of finding the optical signature of oxygen vacancies in the film structure. It was found that a reduction of oxygen content in the film leads to changes in both, structural and optical characteristics. Optical absorption spectroscopy, using nanoKelvin calorimetry, revealed an enhanced absorption in the near-ultraviolet (near-UV) and visible wavelength ranges for films with reduced oxygen content, which was attributed to mid-gap electronic states of oxygen vacancies.

Modeling Hemolytic-Uremic Syndrome: In-Depth Characterization of Distinct Murine Models Reflecting Different Features of Human Disease.

Diarrhea-positive hemolytic-uremic syndrome (HUS) is a renal disorder that results from infections with Shiga-toxin (Stx)-producing . The aim of this study was to establish well-defined refined murine models of HUS that can serve as preclinical tools to elucidate molecular mechanisms of disease development. C57BL/6J mice were subjected to different doses of Stx2 purified from an O157:H7 patient isolate.

Development and validation of an ultrahigh performance liquid chromatography-high resolution tandem mass spectrometry assay for nine toxic alkaloids from endophyte-infected pasture grasses in horse serum.

Endophyte fungi (e.g. Epichloë ssp.

Whole-genome sequencing of a large collection of Myroides odoratimimus and Myroides odoratus isolates and antimicrobial susceptibility studies.

The genus Myroides comprises several species of Gram-negative, non-motile, and non-fermenting bacteria, which have been regarded as non-pathogenic for decades. Multiple recent reports, however, underscore the pathogenic potential that Myroides sp. possesses for humans.

High photon conversion efficiency continuous wave lasing in an optically pumped I hollow fiber gas laser in the visible region.

Continuous wave lasing in the visible spectral region from a molecular iodine-filled hollow core photonic crystal fiber is demonstrated. More than an order of magnitude improvement in photon conversion efficiency has been achieved compared to previous nonfiber-based geometries in this spectral region. The laser shows strong coupling of pump and laser polarization.

Development and validation of an ultrahigh performance liquid chromatography-high resolution tandem mass spectrometry quantification method for hypoglycin A and methylene cyclopropyl acetic acid carnitine in horse serum in cases of atypical myopathy.

Atypical myopathy (AM) is a fatal disease in horses presumably caused by hypoglycine A (HGA) from ingested maple seeds and its active metabolite methylene cyclopropyl acetic acid (MCPA). The aim of this study was the development and validation of a rapid and simple assay for HGA and MCPA-carnitine in horse serum and its application to authentic samples. Identification and quantification were carried out by ultra high performance liquid chromatography-high resolution tandem mass spectrometry (UHPLC-HRMS/MS) with full-scan/data-dependent MS/MS.