HIF-1α regulated pathomechanism of low birth weight through angiogenesis factors in placental infection.

Background: Malaria in pregnancy leads to placental malaria. The primary pathogenesis of the complex fetal implications in placental malaria is tissue hypoxia due to sequestrations of -infected erythrocytes in the placenta. However, the pathomechanism of placental infection has not been thoroughly investigated.

The Relationship Between Fetal Weight with Sequestration of Infected Erythrocyte, Monocyte Infiltration, and Malaria Pigment Deposition in Placenta of Mother Giving Birth Suffering from Plasmodium Vivax Infection.

Background: Malaria in pregnancy can cause fatal complications by parasite sequestration mechanism, which can cause monocyte infiltration in the intervillous space. infection was significantly associated with malaria pigment in the placenta, indicating past subclinical infections.

Objective: This study aimed to determine the mechanism of in the pathogenesis of placental malaria and its relationship with LBW.