Opportunities and limits of cell-based assay miniaturization in drug discovery.

Importance Of The Field: Miniaturization is a significant driver for many life-science applications and a key technology for personalized medicine. Innovations in microfluidics will make ex vivo testing in in vivo-like environment possible, thus, allowing novel pathways for drug discovery.

Areas Covered In This Review: This review covers the application of miniaturization technologies, namely microfluidics for cell-based assay development.