Publications by authors named "Rudenko A"

In the paper, results are presented of investigation into the effects of transcranial electroanalgesia (TCEA), a novel nonmedicamentous method of treatment, on certain neurophysiological parameters in patients with cerebral venous dystonia. TCEA is shown to be an efficient treatment option in the above group of patients.

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Cytostatics and hormones were studied for their effect on biological peculiarities of Escherichia coli--the main agent of inflammatory processes of kidneys and urinary tracts in children and adults. It was established that low doses of glucocorticoids, cytostatics and their combinations lead to changes in morphological properties in the strain of E. coli: M- and R-forms appeared in some variants.

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An algorythm of differential diagnosis conduction of the transplant rejection reaction and the diseases caused by herpes viruses in recipients after the kidney transplantation was elaborated, basing on the analysis of results of the clinical, laboratory, immunological and serological examination methods.

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Investigations were conducted designed to study effects of the complex of vitamins with minerals "Multi-Tabs" (Denmark) as a preventive measure devised to combat influenza during the 1997 influenza epidemic in Ukraine. The article contains epidemiological characterization of the above epidemic. Used in 160 adults and 55 children "Multi-Tabs" has been shown to be an effective means of the influenza and ARD prophylaxis in an epidemic setting both in adults and children.

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Spectrum of microbe agents of acute pyelonephritis has been studied. It is shown that Mycoplasma hominis plays an important role in etiology of acute pyelonephritis besides the already known enterobacteria and Gram-positive cocci. It is also established that mycoplasmal pyelonephritis more often develops in patients with the diseases of urinary blade (cystitis) and genital organs.

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Results of a clinical and microbiological investigation designed to study thienam permit recommending this drug as an urgent agent of choice in acute purulent pyelonephritis. The drug is well tolerated. Among other benefits is extremely high sensitivity of bacteria (pathogenic and conditionally pathogenic) to the medication, achievement of an expected clinical effect within a short time since its therapy institution.

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Polysaccharides of Clavibacter michiganense have been studied for their effect on Mycoplasma infection. It is established that content of T-lymphocytes truthfully increased in the groups of animals whose PS 1 and PS 2 were administered both with protective and medical purpose as compared with that in a group of animals with natural course of mycoplasmosis. Under these conditions the effect of polysaccharides on T-helpers were not evidently expressed, while they exerted considerable effect on T-suppressors, normalizing their high index in the animals infected by Mycoplasma hominis.

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The authors submit results of treatment of patients having suffered from postherpetic pain syndrome (herpetic ganglionitis of the cervical, thoracic, lumbosacral localization, postherpetic intercostal neuralgia, ganglionitis of the trigeminal nerve). In viral diseases, amizone has marked analgetic, antiinflammatory, and immunomodulating effects. The drug is well tolerated by patients, is not associated with side effects under prescribed doses (0.

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An original method for the determination of cell membrane permeability has been developed. Human buccal epithelium cells were treated with Indigo Carmine and the percentage of stained cells was determined. Employing this method, the age-related differences in properties of plasma membrane in cells of human buccal epithelium were demonstrated.

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A comparative analysis was performed of clinical-neurological-hemodynamic-structural changes in the acute phase of hemorrhagic insult (HI) in 56 patients who ranged from 19 to 59 years old. Intracerebral hematomas (ICH) appeared to be more commonly seen. Main emphasis was put on potentialities of Doppler Sonography (DS) in hemodynamic assessment of cerebral bloodflow condition in patients with hemorrhagic insult.

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The paper is concerned with a study into compensatory capabilities of cerebral hemodynamics in patients with atherosclerotic dyscirculatory encephalopathy in constricting lesions of major arteries of the head. A detailed analysis is provided of hemodynamic mechanisms of the natural collateral's work, viz., via anterior communicating artery and conditions for creation of suprablock anastomosis with the internal carotid artery being occluded.

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Administration of laferon to patients stimulates the blood serum interferon formation, with its peak being reached by 24 h. The evaluation done confirmed the therapeutic efficacy of laferon in meningoencephalites. This was manifested by reduction in duration of certain clinical symptoms, timeterms of spinal fluid sanitation, improvement in immunity parameters and increase in the patients' blood serum level of interferon.

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Based on the analysis of findings from clinical and paraclinical investigations (ultrasonic vascular diagnosis, electroencephalography, computerized tomography, angiography) in 244 patients with atherosclerotic dyscirculatory encephalopathy, functional status was studied as were structural alterations in the brain tissue in stenosing lesions of precerebral arteries. The first clinical manifestations of atherosclerotic dyscirculatory encephalopathy in the presence of damage to the vestibular-basilar system were found to be dysfunction of column structures of vestibular apparatus, reticular formation and posterior longitudinal fascicle, and, in the presence of damage to the carotid area, -- dysfunction of cortex of frontal, parietal and temporal lobes of the brain.

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Various aspects of ionizing radiation action on microorganisms and course of endo- and exogenous infections are considered. The immune response is discussed from the standpoint of its significance in development of infectious-inflammatory processes under conditions of radiation of a microorganism and higher radiation background. Quantitative and functional changes in the immune system of the organism subjected to radiation are discussed in detail and peculiarities of these changes under low doses of radiation are shown.

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Five strains of the genus Bacillus used as components of biological preparations i.e. bacterin SL, biosporin, bactisubtil and subalin were tested for their susceptibility to 38 antimicrobial agents, The strains were simultaneously resistant to 5 antibiotics: astreonam, colistin, penicillin, ceftizoxime and cefuroxime.

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Results have been analysed of comprehensive evaluation of 175 patients with discirculatory encephalopathy of atherosclerotic genesis, consisting of inspection of the neck vessels projection, study of neurological status, ultrasonic investigation of the major brain arteries structure and hemodynamics, their angiographic features. At stage I discirculatory encephalopathy subjective complaints predominated, being caused by syndrome of thoracic outlet, steal syndrome, stenosing lesions of brachiocephalic arteries. Encountered more frequently in the middle-aged and elderly patients were affections of several major brain arteries.

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