[Fatal course of virus-associated pneumonia in patient with influenza A(H1N1)].

In 2009 pandemic caused by high-path fluenza A(H1N1), so called "swine" flu was registered in the world. Aphylaxis to this type of influenza lead to pandemic. The authors gave an example of fatal course of influenza A(H1N1)S-OIV in young patient with severe VA-pneumonia, acute respiratory distress syndrome, disseminated intravascular coagulation with progressive respiratory distress secondary to an metabolic syndrome.

[Nanoelectrochemistry of cytochrome P450s: direct electron transfer and electrocatalysis].

The present study demonstrates the direct electron transfer between cytochrome P450 2B4 (CYP2B4), P450 1A2 (CYP1A2), sterol 14alpha-demethylase (CYP51MT) and screen printed graphite electrodes, modified with gold nanoparticles and didodecyldimethylammonium bromide (DDAB). Electrodetection of heme proteins is possible when 2-200 pmol P450/electrode were adsorbed on the surface of nanostructured electrochemical interfaces. Electron transfer, direct electrochemical reduction and interaction with P450 substrates (oxygen, benzphetamine, lanosterol) and inhibitor ketoconazole were analyzed using cyclic voltammetry (CV), square wave (SWV) or differential pulse (DPV) voltammetry, amperometry.

[Combined effect of UHF-hyperthermia and x-irradiation on the growth of sarcoma 45].

Repeated local exposure (6 sessions) of rat sarcoma 45 to ultrahigh-frequency hyperthermia (41.5--42.5 degrees C in the tumor for 30 minutes per session) and x-ray radiation (a single dose of 8 Gy) irrespective of the succession of their application enables complete resolution of the tumor to be attained at the logarithmic stage of its growth.

[Thermal state of the body following exposure to UHF radiation].

A mathematical model of thermal heating of animal exposed to UHF-irradiation is suggested. Besides physical heat transfer between the organism and its surroundings, the model takes into account physiological mechanism of thermal regulation-hypernea and hyperhidrosis. Possible evaluation of exposure limits for microwave irradiation is considered on the basis of the model.

[Temperature reaction and survival of experimental animals exposed to microwaves of different intensity].

Changes of the rectal temperature during the day were determined in CBA mice and Wistar rats subjected to the total body irradiation with microwaves of different intensity. Dependence of these indices on keeping the animals in containers for irradiation and temperature reactions, and survival of the animals after exposure to UHF microwaves of various intensity were investigated. As shown, temperature rise and survival of the animals depended on the current intensity density and the action duration, the rectal temperature elevation during the irradiation; a pronounced reduction of this index following irradiation may be considered as a prognostic sign of affection with the UHF microwave field.