Publications by authors named "Ruchitha Pailla"
Hereditary spherocytosis (HS) is a genetic disorder characterized by the presence of spherocytes, which are abnormally shaped red blood cells, leading to hemolytic anemia. While HS is not uncommon in hematology, it can present significant diagnostic and therapeutic challenges in its late stages, particularly when complicated by severe cholestasis. We report a case of a 48-year-old male presenting with jaundice and abdominal pain, initially diagnosed with cholecystolithiasis and moderate splenomegaly.
View Article and Find Full Text PDFBackground Chronic obstructive pulmonary disease (COPD) is characterized by periods of exacerbations and seasonal variations due to the recruitment of inflammatory cells. Various cells, such as neutrophils, lymphocytes, and the inflammatory mediators released by them, play a role in its pathogenesis. The current study was conducted to determine the role of the neutrophil-to-lymphocyte ratio (NLR) as a marker in acute exacerbation of COPD (AECOPD).
View Article and Find Full Text PDFAim: The study aimed to know the changes in spirometry parameters in chronic smokers and evaluate how the presence of type 2 diabetes mellitus (T2DM) affects their lung function.
Materials And Methods: A prospective, cross-sectional, observational study was done for 12 months at a tertiary care hospital in the western region of Maharashtra State in India. Two groups of patients and one group of healthy volunteers aged 18 years or more were studied (with 50 in each group, = 150).
Background and aim Type 2 diabetes mellitus (T2DM) is associated with several infections due to hyperglycemia and impaired immunity. This study aims to analyze the clinical and microbiological profile of critically ill T2DM patients with sepsis due to gram-negative bacteria (GNB). Materials and methods A prospective cross-sectional observational study was conducted at Dr.
View Article and Find Full Text PDFArticle Synopsis
- - The study focused on understanding how liver cirrhosis affects lung function, specifically by evaluating arterial blood gas (ABG) levels and pulmonary function tests (PFT) in diagnosed patients over a two-year period.
- - A total of 64 patients participated, with a majority experiencing respiratory symptoms like breathlessness and pleural effusion; significant findings included low pH and oxygen levels, particularly among more advanced cases (Child Pugh Stage C) and patients with hepatopulmonary syndrome (HPS).
- - The research concluded that pulmonary dysfunction is prevalent in advanced liver cirrhosis, with those having HPS displaying poorer lung function metrics compared to others, indicating a link between liver and respiratory health.
Tuberculosis (TB), although a preventable and curable disease, accounts for a high burden of morbidity in developing countries like India. Lung scarring and damage is a common sequel of pulmonary tuberculosis (PTB). Here, we report an interesting case of a patient with a history of PTB diagnosed four years ago and on subsequent visits was diagnosed with squamous cell carcinoma of the lung at the site of the TB scar.
View Article and Find Full Text PDFBackground And Aims: Liver cirrhosis influences gonadal hormone metabolism by multiple mechanisms and causes gonadal dysfunction. This study aimed to study sex hormones in males with cirrhosis and determine their correlation with prognostic scores.
Methods: An observational study was conducted between October 2019 and August 2021 in India.