Publications by authors named "Ruchira Shukla"

Article Synopsis
  • Genomic methylation shows promise as a tool for identifying oral potentially malignant disorders (OPMDS) and oral cancer, which could enhance understanding of cancer mechanisms and lead to new therapies.
  • A study involving 112 patients with premalignant and malignant oral lesions analyzed saliva samples to investigate genetic markers like p16, DAP-K, and MGMT using advanced DNA methylation technology.
  • Findings indicated that 12.7% of oral cancer lesions displayed methylation of the examined genes, with higher rates of co-methylation, suggesting these genetic markers can aid in predicting the progression of oral cancer and patient outcomes.
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Haematological profile of patients with oral sub mucous fibrosis (OSMF) and its correlation with the severity of OSMF is evaluated. The study comprised of sixty participants with clinical diagnoses. They were divided into smaller groups based on the OSMF stage.

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Background: This study examines the surface changes of stainless steel miniplates and screws after their retrieval from patients who underwent maxillofacial trauma and orthognathic surgery. The assessment focuses on comparing the alterations in these materials, aiming to contribute to our understanding of their durability and performance in clinical settings.

Materials And Methods: A total of 60 stainless steel miniplates and screws were collected from 30 patients who had previously undergone either maxillofacial trauma or orthognathic surgery.

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It is of interest to compare conventional lateral window technique, trans-alveolar technique with minimally invasive technique like modified trephine technique and antral membrane balloon elevation technique for sinus floor elevation in placement of dental implants. The current study included 140 participants (191 dental implants) who had maxillary posterior edentulous regions and had low sinuses and insufficient alveolar ridges but had chosen an implant-retained prosthesis. The minimally invasive techniques of sinus augmentation can be suitable alternative to conventional traumatic techniques due to low incidence of pain, gingival swelling.

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