Publications by authors named "Ruchira Banerjee"
Article Synopsis
- - Bile acid transporters (BATs) are important proteins that help move bile acids in the body, especially in the liver, kidney, and small intestine, and are linked to fat absorption and liver function.
- - Altered levels of bile acids are associated with cancer, but the specific role of BATs in cancer progression—like tumor growth and spread—has not been fully explored yet.
- - This review suggests that researching BATs further could lead to new cancer treatments, especially for liver and gastrointestinal cancers, and encourages targeting these transporters with different techniques for potential therapies.
Despite the significant amount of experimental data available on trehalose, the molecular mechanism responsible for its intracellular stabilising properties has not emerged yet. The repair of cellular homeostasis in many protein-misfolding diseases by trehalose is credited to the disaccharide being an inducer of autophagy, a mechanism by which aggregates of misfolded proteins are cleared by the cell. In this work, we expressed the pathogenic N-terminal fragment of huntingtin in Δnth1 mutant (unable to degrade trehalose) of Saccharomyces cerevisiae BY4742 strain.
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