Cannabidiol on 5-FU-induced oral mucositis in mice.

Purpose: The aim of this study was to evaluate the clinical, histological, hematological, and oxidative stress effects of cannabidiol (CBD) in mice with induced oral mucositis.

Methods: We used 90 mice of the CF-1 strain in which oral mucositis was induced using a protocol with 5-fluorouracil (5-FU) chemotherapy. The animals were divided randomly into 10 study groups.

Doxycycline: An option in the treatment of ulcerated oral lesions?

What Is Known And Objectives: In addition to its antimicrobial effect, doxycycline has potent anti-inflammatory activity. In view of these pharmacological characteristics, its use in the management of inflammatory, autoimmune and granulomatous diseases has been proposed. The objective of this study was to investigate, through a systematic literature review, the effect of doxycycline on pain and healing of ulcerated lesions of the mouth.

Local and systemic tissue response submitted to injection of 2 and 30% polymethylmethacrylate in rats' tongue.

Introduction: Adverse effects on the oral mucosa after the use of dermal fillers have been reported due to their increased use for facial aesthetics.

Objective: This study aimed to evaluate, clinically and histologically, the local and systemic effects of two concentrations of polymethylmethacrylate (PMMA) dermal filler in rats.

Material And Methods: Fifty-four female rats were allocated into three treatment groups (2% PMMA, 30% PMMA and 0.

Use of polymethylmethacrylate as permanent filling agent in the jaw, mouth and face regions--implications for dental practice.

Objectives: This article is a review of PMMA focusing on its properties, indications, contra-indications and adverse effects.

Background: search to remain young is a constant attitude among Brazilians. The low cost of filling agents have stimulated its indiscriminate use, especially the bioplasty (non-incisional method).